Protein Info for GFF2736 in Variovorax sp. SCN45

Annotation: Uncharacterized MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 403 signal peptide" amino acids 1 to 38 (38 residues), see Phobius details transmembrane" amino acids 54 to 76 (23 residues), see Phobius details amino acids 85 to 104 (20 residues), see Phobius details amino acids 111 to 131 (21 residues), see Phobius details amino acids 143 to 164 (22 residues), see Phobius details amino acids 171 to 189 (19 residues), see Phobius details amino acids 210 to 233 (24 residues), see Phobius details amino acids 252 to 272 (21 residues), see Phobius details amino acids 279 to 298 (20 residues), see Phobius details amino acids 303 to 323 (21 residues), see Phobius details amino acids 339 to 360 (22 residues), see Phobius details amino acids 367 to 385 (19 residues), see Phobius details PF07690: MFS_1" amino acids 23 to 352 (330 residues), 129.7 bits, see alignment E=6.3e-42

Best Hits

KEGG orthology group: None (inferred from 66% identity to avn:Avin_35870)

Predicted SEED Role

"Major facilitator family transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (403 amino acids)

>GFF2736 Uncharacterized MFS-type transporter (Variovorax sp. SCN45)
MSFTHPNPSPPRARLPLSGLLALAAASFITILTEAMPAGLLPQIGASLAVTPALVGQLVT
VYALGSLVAAIPLVAFTRGWRRRPLLMLAIGGFAIVNTVTALSHSYPLTLAARFFAGVFA
GLLWALVAGHAGRMVPPSMQGRAIAVAMLGAPLALSLGIPAGTLLGTGVGWRPAFLVMSA
LSVLLLGWVRWQVPDFPGQEAGRRQSVKRVFLLPGVRPVLGVMLAFVLAHNILYTYIAPF
LAHAGLGARVDLVLLVFGTASLAGIWVTGVLIDRWLRELVLASTAVFGLTALLLGTAAGS
TAAVYVGVAIWGLAYGGAGTLFQTASAQAAGESADVAQSMVVTVWNIAIAGGGLLGGLLL
QGGGAGALPWSLLVLLVPALWLTWRAGAHGFPGSRGVAGATAR