Protein Info for GFF2724 in Variovorax sp. SCN45

Annotation: FIG01220323: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 356 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF02129: Peptidase_S15" amino acids 58 to 307 (250 residues), 42.8 bits, see alignment E=8.4e-15 PF01738: DLH" amino acids 66 to 181 (116 residues), 37.6 bits, see alignment E=2.9e-13 PF12146: Hydrolase_4" amino acids 98 to 326 (229 residues), 30.8 bits, see alignment E=2.9e-11

Best Hits

KEGG orthology group: K06889, (no description) (inferred from 75% identity to ypy:YPK_2191)

Predicted SEED Role

"FIG01220323: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (356 amino acids)

>GFF2724 FIG01220323: hypothetical protein (Variovorax sp. SCN45)
MNIKTLGLTCVAGAVGLISSVAVAADYKKNPFTLAYDGAITENAKGAVNITPVKYKLDGL
DIVANVYTPANYSPARKYPAIVVAHPNGGVKEQVAGLYAQRLADQGYIAIAADAAYQGGS
GGQPRYVDKPANRVEDIHGMADFLSQYAGVDAARIGLLGICGGGGYSLKAAQSDKRFKSV
ATLSMFNSGRVRRNGYMDSQLDTVQERLRQASDARARQAAGGEAAYANTAKLTDEQIAKL
PFALYRQGMAYYGKTHFHPNSSGAFTTSSLLDLMSWDATDNIDLIDQPLLMMAGSNADSL
YMSQGAMAKATGTKDKELFLIDGATHIETYWKPEYVNQAVAKLKDFFGRTLVASAG