Protein Info for PS417_13875 in Pseudomonas simiae WCS417

Annotation: circadian clock protein KaiC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 499 PF06745: ATPase" amino acids 13 to 239 (227 residues), 143.3 bits, see alignment E=4.1e-45 amino acids 255 to 473 (219 residues), 106.5 bits, see alignment E=7.3e-34

Best Hits

KEGG orthology group: K08482, circadian clock protein KaiC (inferred from 95% identity to pfs:PFLU3024)

Predicted SEED Role

"KaiC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U9W1 at UniProt or InterPro

Protein Sequence (499 amino acids)

>PS417_13875 circadian clock protein KaiC (Pseudomonas simiae WCS417)
MSTSNELLSEKAATGIEGLDDILAGGLSRSHLFLLEGEPGTGKTTVALHFLQAGAKNGET
SLYITLSETERELRQGATSHGWDLDDNIHIFELTPPESLLNAEHQQSLLYSSDLELGEAT
RQIFEVVERVKPTRVVVDSLSEIRLLAQSSLRYRRQILAIKHYFVRYDATVLLLDDLTTE
SLDKTVHSVAHGVIRLEELTPNYGAERRRVRVVKYRGQKYRGGFHDFTIMQGGVHVFPRL
VAAEHRGGYNRQTLTSGIRELDALLGGGIETGSSSLILGPAGTGKSLISMIFAAAAVARG
EKAALFIFDEELGLLFERMKNMGIDLAALQATGNLFIEQVDAAELTPGEFSHRVRRCVDE
RGIKTVVIDSINGYQAAMPEENALILHMHELLLYLNRRGAATFMTVAQHGLVGDMQAPVD
ITYLADTVILLRYFEAIGEVRRAISIIKKRTGTHESTIREYRIGSRGMTVGEPLNNFQGV
LRGIPTYMGAGSPLLKDEG