Protein Info for GFF2717 in Sphingobium sp. HT1-2

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 838 signal peptide" amino acids 1 to 38 (38 residues), see Phobius details PF07660: STN" amino acids 71 to 110 (40 residues), 29.2 bits, see alignment 9.9e-11 PF07715: Plug" amino acids 175 to 273 (99 residues), 64.2 bits, see alignment E=2.3e-21 TIGR01783: TonB-dependent siderophore receptor" amino acids 177 to 837 (661 residues), 345.3 bits, see alignment E=4.1e-107 PF00593: TonB_dep_Rec_b-barrel" amino acids 356 to 806 (451 residues), 187.4 bits, see alignment E=1.3e-58

Best Hits

Predicted SEED Role

"TonB-dependent siderophore receptor" in subsystem Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (838 amino acids)

>GFF2717 hypothetical protein (Sphingobium sp. HT1-2)
LTDVSILGQNFGRALAIGLLASTVMGAALLSPAMAQASPNSAQRRINVPAQPLTDAVILF
GRQSGVEVTAGSDLLNGKISSAVAGNFAPAEALSRLLSGTGLTFRFIGPKSVELHPAPQA
ANGTVQLGPVRVEGADGGSGSGSSAGITSDPVATEASGSYTITAMSTATKLLLSPRETPQ
SLTVVTRQRIEDQGLATLSDVVRATPGLYLTKWGGERYRFNARMFQLDNLMIDGMPVQYE
EAALSTGILDMYDRVEVVRGAAGLMEGAGTPAGSINLVRKRPTRETQAIFTLSAGSWNNF
LGTMDVGGAVNSAGTLRTRAVVTYQDKDSFIDDYHNQRMSLYGIVEADLGSSTLLTVGAS
YSNEDNPGVDWNGLGTAADGSFLDIARSTRMSPSWSYWDKKSATYFANLDHEFGNGWKAR
LTATAIQSEMSMIGTFLSYATSTAGETRFNLGGAALAYHYDRDQLSLDGYASGPLTLFGQ
THELVVGGSYRKATWDDIGAPTDFTAVSFDPLDWDPRSVPAPTITGDWTMYLRDQKREQI
GVYSTARLTVAEPLTLILGGRFDWFKQELANGWAGAIYSTADYKVKGQFTPYVGVVYDFH
RNHSLYASWTRIFNPQNNLTRTGAIIAPQEGANYEVGVKGSYWDGHLNTSLALFQIELTN
LPMALLASECAAGLTACYAPSGKVRSRGVEFEVSGELANGWQLSGGYTYNTAKHLSSSSY
NPTGIYTDGTRYGTNLPRGLFKLSTTYNLPGAFDRWTLGGTLQAQSKIYSAPYGGLVQQD
GYALLDLSIKYAVSSRATVTVNVNNVFDKYYYENIGAPTGSNFIGAPRNVLATLRYKI