Protein Info for GFF2711 in Sphingobium sp. HT1-2

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 572 transmembrane" amino acids 485 to 503 (19 residues), see Phobius details PF02384: N6_Mtase" amino acids 29 to 218 (190 residues), 21 bits, see alignment E=1.9e-08 PF07669: Eco57I" amino acids 144 to 246 (103 residues), 87 bits, see alignment E=1.6e-28

Best Hits

Swiss-Prot: 67% identical to MTP7_PSEAI: Modification methylase PaeR7I (paeR7IM) from Pseudomonas aeruginosa

KEGG orthology group: None (inferred from 67% identity to plu:plu2710)

Predicted SEED Role

"Modification methylase PaeR7I (EC 2.1.1.72)" (EC 2.1.1.72)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.72

Use Curated BLAST to search for 2.1.1.72

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (572 amino acids)

>GFF2711 hypothetical protein (Sphingobium sp. HT1-2)
MTKINLATVLREPSFPDLCPVIEAVDAMANAGIEERGAIFTRREVVEFILDLSGYNAAAP
LHTLRLLEPSFGFGDFLLPAIDRLLVAWKRSGTEPGALSDAIRAVELHRASFDRTHALVV
QKLRAAGVGLRDAESLADQWLMQGDFLLVPLSGKFDFVIGNPPYVRQELIPSALMAEYRA
RYRTIYDRADIYIPFIERSLDLLAKSGKLGFICADRWMKNRYGGPLRAMVANGFHLSVYV
DMVNTPAFHQEVVAYPAITIIGREKSGLTRIAHRPEISDSALSLLAAALRSPDTPSPASG
VRELQAVTSGAEPWILETSDQLALVRRLESQFPLIEEAGCKVGIGVATGADKAFIGPFDA
LDVEASRKLPIVMTRDIMDGSVKWRGQGVVNPFGDDGKLVKLDQFPKLKRYLEERRDQIA
GRHVAQKAPANWYRTIDRIYPELADEPKLLIPDIKGAAHIVFEEGSLYPHHNLYFITSET
WDMRALQAVLLSGIARLFVATYSTRMRGGYLRFQAQYLRRIRLPDWKDVTPKMRQALKKA
AEAGDVEACNNLTFDLYDLSAQERATLGGAEK