Protein Info for GFF2702 in Variovorax sp. SCN45

Annotation: FAD-dependent oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 460 PF01946: Thi4" amino acids 14 to 64 (51 residues), 27.7 bits, see alignment 6.9e-10 PF00890: FAD_binding_2" amino acids 22 to 205 (184 residues), 40.5 bits, see alignment E=9.8e-14 PF01134: GIDA" amino acids 22 to 55 (34 residues), 24.6 bits, see alignment 5.8e-09 PF07992: Pyr_redox_2" amino acids 22 to 54 (33 residues), 28 bits, see alignment (E = 6.9e-10) PF01266: DAO" amino acids 22 to 96 (75 residues), 29.5 bits, see alignment E=2.6e-10 PF12831: FAD_oxidored" amino acids 22 to 357 (336 residues), 220.8 bits, see alignment E=1.8e-68 amino acids 359 to 431 (73 residues), 77.9 bits, see alignment E=4.6e-25 PF13450: NAD_binding_8" amino acids 25 to 60 (36 residues), 30.2 bits, see alignment 2e-10

Best Hits

KEGG orthology group: None (inferred from 78% identity to vei:Veis_3505)

Predicted SEED Role

"FAD dependent oxidoreductase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (460 amino acids)

>GFF2702 FAD-dependent oxidoreductase (Variovorax sp. SCN45)
MSRIGDWMQEPAHDVRVAAESDVVVVGGGPAGQAAALAAARNGASVTLLERYNHLGGLAS
GGMVLVLDDMWDSHQQEISVRGICLEMIERMSALGLAEYPRQHEWGTLPESVRRWKRWGT
YDFHSKEKPHPICFAAAFDPDAWKRTSLEMVLQAGIELRLHSWFSRTLVEDGKVKGVVCE
TKGGREAILGKVVIDTTGDLDVAASAGAPHISGSYIVTTVFRLGGVDTEEAERFERDEPV
AWQALDREIKHMLGGAWEAWWLKTPLPGVVWCNCPHMPGLDGLKVSDLTRAEVQGRATIH
KVIEFVRAKLPGFGKCTLIDMAPQTGIRQTRLLEGAYVMTKEDVSQRTRFEDSVARGRDY
YYPYRTLLPRSVENLLVAGRHYSATSAAQKISREIPPCMAMGEATGTAAALALNAGVTVR
EVDIAKLQKTLRAQGADPGDQKGPNADVPAIARSFAKEAA