Protein Info for GFF2697 in Xanthobacter sp. DMC5

Annotation: Circadian clock protein kinase KaiC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 507 PF06745: ATPase" amino acids 16 to 242 (227 residues), 141.5 bits, see alignment E=2e-44 amino acids 258 to 475 (218 residues), 116.2 bits, see alignment E=1.1e-36 PF13481: AAA_25" amino acids 255 to 379 (125 residues), 37.4 bits, see alignment E=1.5e-12

Best Hits

KEGG orthology group: K08482, circadian clock protein KaiC (inferred from 75% identity to rle:RL2732)

Predicted SEED Role

"KaiC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (507 amino acids)

>GFF2697 Circadian clock protein kinase KaiC (Xanthobacter sp. DMC5)
MESTTKGEDSYTRKARTGIEGLDEVLSGGFTSGHVFLLEGNPGTGKTTIALRFLLEGAAA
GERCLYITLSETEQELRNGAAAHGWTIDGNIEVFVLVPAESLLDGDQQQSLLYASDLELG
EATAAIFQAFERLRPSRVVLDSLSEIRLLAQSSLRYRRQILALKHYFARHGATVLLLDDR
TTETSDKTAHSVVHGVILLEELAPNYGTERRRLRVSKYRGQAFRGGFHDFAIRTGGVVVF
PRLVASEHRQSLARTQLKSDVPELDALLGDGIEQGSSTLILGPAGTGKSIFALQFAVAAC
RRGEAASFFVFDEELDLLFDRARAMGFDLRALRDAGLLHIEQLDAAEMSPGEFAQRTRNQ
VDKAQAKVVVIDSLNGYQAAMPEEHSLILHIHELIQYLNRRGANTFLTVAQHGLVGEMRA
PVDVTYLADTVILLRYFEAMGKLRRAVSIIKKRNGRHEDTIREFRITDRGLSLGKPLEEF
QGILRGVPTFVGAGQPLLSEPASNGHL