Protein Info for GFF2680 in Variovorax sp. SCN45

Annotation: Protein of unknown function DUF1058

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 153 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF06347: SH3_4" amino acids 36 to 85 (50 residues), 38.4 bits, see alignment E=1.3e-13 amino acids 98 to 152 (55 residues), 48.3 bits, see alignment E=1.1e-16 PF08239: SH3_3" amino acids 38 to 86 (49 residues), 36 bits, see alignment E=9.8e-13 amino acids 100 to 148 (49 residues), 46.9 bits, see alignment E=3.8e-16

Best Hits

KEGG orthology group: None (inferred from 80% identity to vap:Vapar_3400)

Predicted SEED Role

"Protein of unknown function DUF1058"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (153 amino acids)

>GFF2680 Protein of unknown function DUF1058 (Variovorax sp. SCN45)
MVRFSRWSALLLAFVLSWVALPSAFAAQQQMVSVAVKTLNMRTGPGPRYETHWTVSRGYP
FKVIGRKGDWLHVSDFEGDKAWVFRSMTNKTPHHVVKAQVANLRRAPNTRSPVMKKAGYG
DVLRTIERRGDWIKVRHEGGTTGWVQKRLTWGW