Protein Info for GFF2650 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Zinc transport protein ZntB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 327 transmembrane" amino acids 269 to 290 (22 residues), see Phobius details amino acids 301 to 321 (21 residues), see Phobius details PF01544: CorA" amino acids 38 to 323 (286 residues), 251.6 bits, see alignment E=5.1e-79

Best Hits

Swiss-Prot: 100% identical to ZNTB_SALPK: Zinc transport protein ZntB (zntB) from Salmonella paratyphi A (strain AKU_12601)

KEGG orthology group: K03284, metal ion transporter, MIT family (inferred from 99% identity to set:SEN1375)

MetaCyc: 92% identical to Zn2+:H+ symporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-346

Predicted SEED Role

"Zinc transport protein ZntB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (327 amino acids)

>GFF2650 Zinc transport protein ZntB (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
VEAIKGSDVNVPDAVFAWLLDGRGGVKPLEDNDVIDSQHPCWLHLNYTHPDSARWLASTP
LLPNNVRDALAGESSRPRVSRMGEGTLITLRCINGSTDERPDQLVAMRLYMDERFIVSTR
QRKVLALDDVVSDLQEGTGPVDCGGWLVDVCDALTDHASEFIEELHDKIIDLEDNLLDQQ
IPPRGFLALLRKQLIVMRRYMAPQRDVYARLASERLPWMSDDHRRRMQDIADRLGRGLDE
IDACIARTGIMADEIAQVMQESLARRTYTMSLMAMVFLPSTFLTGLFGVNLGGIPGGGWR
FGFSLFCILLVVLIGGVTLWLHRSKWL