Protein Info for GFF2643 in Xanthobacter sp. DMC5

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 signal peptide" amino acids 1 to 44 (44 residues), see Phobius details PF03524: CagX" amino acids 120 to 343 (224 residues), 240.1 bits, see alignment E=9.5e-76 TIGR02775: P-type conjugative transfer protein TrbG" amino acids 121 to 331 (211 residues), 278.6 bits, see alignment E=1.3e-87

Best Hits

KEGG orthology group: K03204, type IV secretion system protein VirB9 (inferred from 95% identity to xau:Xaut_0603)

Predicted SEED Role

"Conjugative transfer protein TrbG" in subsystem Type 4 secretion and conjugative transfer

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (350 amino acids)

>GFF2643 hypothetical protein (Xanthobacter sp. DMC5)
MTPAIRNSGRPAFRGLFFPAFRKSSLPLLLICTSALAGCATFAKPPEIEYDDAPPAVFKA
EPPGPVRIVELPKPLPLPGQLKPVGKDGKAEPEAADPAIRVNQANAAARVQPVRNGFINS
MQVYPFVEGALYQVYAAPGQVTDIALQPGEQLVGTGPVAAGDTVRWIIGDTESGAGAAKQ
VHILVKPTRPDLTTNLVINTNLRTYHMELRSTEKTYMASVSWQYPQDQLIALRRQNAEAA
VVQPVATGIDLTKVNFRYEVSGDRAPWRPLRAFDDGQQVFIEFPRGIAQGEMPPLFVVGP
QGDTSELVNYRVRGSYMIVDRLFAAAELRFGADKAQKRVRISRTDGRPVL