Protein Info for GFF264 in Variovorax sp. SCN45

Annotation: Efflux transport system, outer membrane factor (OMF) lipoprotein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 536 TIGR01845: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family" amino acids 36 to 504 (469 residues), 424.7 bits, see alignment E=2.2e-131 PF02321: OEP" amino acids 104 to 291 (188 residues), 75.5 bits, see alignment E=2.4e-25 amino acids 322 to 502 (181 residues), 110.3 bits, see alignment E=5.1e-36

Best Hits

KEGG orthology group: None (inferred from 57% identity to bph:Bphy_2409)

Predicted SEED Role

"RND efflux system, outer membrane lipoprotein, NodT family" in subsystem Multidrug Resistance Efflux Pumps

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (536 amino acids)

>GFF264 Efflux transport system, outer membrane factor (OMF) lipoprotein (Variovorax sp. SCN45)
MPIQENKASEDHPIEPRAVAARRLARWPVQGAVLGTALLLSACAVGPDFKTPELPAAAQA
PDYTPAPMPSRTVQAEGPAGQAQELVAGRDIPAQWWDVFRSEPLDQLIRASLAQSPTLAS
AQAALRQAEATYEAKTGNLWPQVSAQLGVQRERASEISTQVPGGQLLTLYNASVNVSYNL
DVFGGTRRQIEGAQAAVDTQRYQVEAVYLTLTSNLVTTAIREASLRAQLQATREVLQAQT
EQLNVIEKQFDTGAIPKSIVLQQRTQVAQTQATLPPIEKALAQTRHQLAVFAGRLPSEAG
LPEFDLASLSLPQALPLSLPSELARQRPDVRASEAQLHQASAAVGVATANLYPQIQLSAS
YGNNALRARDLFTGPTTLWNIGAGLTQPIFNGGALRAQQRAAVAAYDSAAAQYRNTVLGA
FQNVADALRALELDAIALQNQAAAESLARQSLDLSTAQFRAGAVSYVTLLTAQQAWLQTH
TALVQAQAARYADTAALFQALGGGWWNRAELANATLSPTVPSAPAAATTTAAPVRN