Protein Info for GFF2622 in Variovorax sp. SCN45

Annotation: Putative transport protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 562 transmembrane" amino acids 12 to 27 (16 residues), see Phobius details amino acids 36 to 56 (21 residues), see Phobius details amino acids 62 to 81 (20 residues), see Phobius details amino acids 92 to 113 (22 residues), see Phobius details amino acids 159 to 181 (23 residues), see Phobius details amino acids 387 to 405 (19 residues), see Phobius details amino acids 411 to 430 (20 residues), see Phobius details amino acids 451 to 469 (19 residues), see Phobius details amino acids 475 to 497 (23 residues), see Phobius details amino acids 539 to 561 (23 residues), see Phobius details TIGR03802: aspartate-alanine antiporter" amino acids 2 to 562 (561 residues), 775.5 bits, see alignment E=3.2e-237 PF06826: Asp-Al_Ex" amino acids 15 to 179 (165 residues), 112.3 bits, see alignment E=2.2e-36 amino acids 391 to 559 (169 residues), 119.4 bits, see alignment E=1.4e-38 TIGR01625: AspT/YidE/YbjL antiporter duplication domain" amino acids 394 to 546 (153 residues), 83 bits, see alignment E=2e-27

Best Hits

KEGG orthology group: None (inferred from 80% identity to mms:mma_1083)

Predicted SEED Role

"putative transport protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (562 amino acids)

>GFF2622 Putative transport protein (Variovorax sp. SCN45)
MEWLHELFKKSPEMALFLSLAVGYWIGKIKFGKFQLGGVAGSLLVAVVVSQVGVQVDGGV
KAVLFALFIYAVGFESGPQFFSSLGRQSIKEIILAAVMAATGLATVVVMAKLFGLDKGLA
AGVAAGGLTQSAIIGTAGDAIGKLGLEAAETARLQGNVAIGYAVTYVFGSFGAIIVCVNI
LPKLMGRTIRDDAIAAETAMQAGVKVLGPDQEEAAPSLVGRIYELTSDPKRTVADIENAN
PATTITIERVKRDGKFVEVSPELVLRQGDIVLAVGRRDAVVANAPLLGKEVYAVDGMELT
MQKREIVLTNKEFEGKTVDVIRKATAGGVRHGIFVVQLSRMGKVLPMKPDTVVQAGDLVS
IFGAEQDVKRVAAIVGDVIVPSAKTDFVYLGAGLVVGLLVGLLSVKIGNIPLTLGAGGGA
LLAGLLFGWYRAKKQTFGALPPSAVQLLKDLGLAGFVVVVGLSSGLQAVQTIKQLGLTIF
GVGVVVTIVPMLLTMLFGRYVLRYDNTAVFAGALSGSRSANPAFGEVLDKAENSIPTVPF
AITYALANVFLTLLGPLIVALV