Protein Info for GFF2609 in Variovorax sp. SCN45

Annotation: Fructose ABC transporter, ATP-binding component FrcA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 265 PF00005: ABC_tran" amino acids 26 to 183 (158 residues), 108.4 bits, see alignment E=2.3e-35

Best Hits

Swiss-Prot: 66% identical to FRCA_RHIML: Fructose import ATP-binding protein FrcA (frcA) from Rhizobium meliloti

KEGG orthology group: K10554, fructose transport system ATP-binding protein (inferred from 95% identity to vap:Vapar_3352)

Predicted SEED Role

"Fructose ABC transporter, ATP-binding component FrcA" in subsystem Fructose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (265 amino acids)

>GFF2609 Fructose ABC transporter, ATP-binding component FrcA (Variovorax sp. SCN45)
MNVVANPKIVMQAKGLVKRYGQVTALDGVDFELREGEILAVIGDNGAGKSSLIKALSGAV
VPDEGQILLDGKPVNFRNPLDARRAGIETVYQDLAVAPAMTIYENLFLGRELRRPGFMGN
VLRMLDKKKMLSESTARMADLKVGIQSMTQAVETLSGGQRQCVAVARSAAFARHVVIMDE
PTAALGVKEGNMVLELIRRVRDRGLPVVLISHNMPHVFEVADRIHVARLGRRAAVLDPKK
ISMSDTVAVMTGAMTAEQLPAEAHA