Protein Info for GFF2606 in Variovorax sp. SCN45

Annotation: Tripartite tricarboxylate transporter TctC family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 338 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details PF03401: TctC" amino acids 124 to 332 (209 residues), 76.8 bits, see alignment E=1.1e-25

Best Hits

KEGG orthology group: K07795, putative tricarboxylic transport membrane protein (inferred from 87% identity to vap:Vapar_3334)

Predicted SEED Role

"Tricarboxylate transport protein TctC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (338 amino acids)

>GFF2606 Tripartite tricarboxylate transporter TctC family (Variovorax sp. SCN45)
MPAPLHANRRHALRALSALLVPASLRAAAADDPSMDAADCVIPAKAGGGFALTCALARDA
LQAVRPGRPPLAQRYLPGGIGAVAFDRIATGKLGGPGTLVAFSSGSLLNLAQGRFGPHPP
SAVRWIATLGTDYGVIAVHRDSPFKRLQDLVAALRQDPSRIAFGAGGTVGSQDWVKAALL
VRAAGRDHKAMRFVSFEGGGDALSALQGKHVDAFPGDAAEALQAIAGGAAVRLLAVLSDE
RLGGGLTGVPTAREQGVDLVWPTVRGLYLSADVPEAAVRAWTAAFREASAAPGYAALLER
HGLYPFALTGTALDDYVQAQIAAYRKLADGLGLRRWPS