Protein Info for PS417_13230 in Pseudomonas simiae WCS417

Annotation: cytochrome P450

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 392 PF00067: p450" amino acids 165 to 361 (197 residues), 69.4 bits, see alignment E=1.4e-23

Best Hits

Swiss-Prot: 47% identical to MYCG_MICGR: Mycinamicin IV hydroxylase/epoxidase (mycG) from Micromonospora griseorubida

KEGG orthology group: None (inferred from 52% identity to amd:AMED_7018)

MetaCyc: 47% identical to mycinamicin IV hydroxylase/epoxidase (Micromonospora griseorubida)
1.14.13.-; 1.14.13.-; 1.14.13.-

Predicted SEED Role

"putative cytochrome P450 hydroxylase" in subsystem Nitric oxide synthase

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7TXH3 at UniProt or InterPro

Protein Sequence (392 amino acids)

>PS417_13230 cytochrome P450 (Pseudomonas simiae WCS417)
MTPLDYPFNCFTDLKLAEPYRHAQQAPGLLRIQMPIGAPAWLATRYDDVRLVLGDRRFSR
SEAFRRDDSPRAFPRIAGGIVMMDPPQLTRIRSRAAQAFTRRRVEALRPHARDYAHQLID
RMLAAGPPADLVNDYALPLPLALICELLGVPVQDRDRFKVWNDSLLSTRTEDAAQTQRHL
GELAAYIKGLVAERRREPRDDFMTALTQTDDKGESLNEEQLLLLCIAILVAGYEGSAAQI
PNFIQVLLDNPTQWQQLKADPEQIPQAVEELLRYIPLASAAMFVHYALEDIQVGETLVRQ
GDAVFASIGAANHDPARFENPQALDLHRDASGHFGFGHGLHHCIGSALARVELQEALHAL
VVRLPDLQRCGEVQWKTATFFRGAHCLPVTWS