Protein Info for PS417_13225 in Pseudomonas simiae WCS417

Annotation: thiazolinyl imide reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 381 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details TIGR01761: thiazolinyl imide reductase" amino acids 7 to 347 (341 residues), 331.2 bits, see alignment E=5e-103 PF01408: GFO_IDH_MocA" amino acids 9 to 125 (117 residues), 75.5 bits, see alignment E=6e-25 PF21390: Irp3-like_C" amino acids 153 to 248 (96 residues), 57.6 bits, see alignment E=1.5e-19

Best Hits

Predicted SEED Role

"iron aquisition yersiniabactin synthesis enzyme (Irp3)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UKW6 at UniProt or InterPro

Protein Sequence (381 amino acids)

>PS417_13225 thiazolinyl imide reductase (Pseudomonas simiae WCS417)
MSRPPVRKRVVIAGTAFGRIYLQALARAQADYELVGILSRGNAYSRACAAHYGVPLYEAV
EQVPDDVDIACVVVRSGATGGAGSELAQHLLRRGIHVLQEHPVHHREIAACMQAARQGRA
AYAVNTLYPNILAIRRFLTVAEYLREQQGLAYIDAACNSQVAYPLLDILGRLAGGMRPWV
FAAPGAGVGTQPFTRLNARFNGVPISLRIQNQVHPQDPDNHSFLLHRLEVGCEAGVLSLG
DTHGPVLWNPRLHAPRDNTDRLIMAGPGSERLAGPTMVVLDPQTPASYHQVFNQVWPDAV
TVALGELCRDIDEPARRLRSGVWATEVSMAWREMNSLIGMPELIEPPVPRALPLAELQAR
ADAVHPPCGDDTAQLLGALPF