Protein Info for GFF259 in Xanthobacter sp. DMC5

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 299 TIGR00338: phosphoserine phosphatase SerB" amino acids 78 to 287 (210 residues), 202.1 bits, see alignment E=8.6e-64 PF00702: Hydrolase" amino acids 84 to 258 (175 residues), 49.2 bits, see alignment E=1.4e-16 TIGR01488: HAD phosphoserine phosphatase-like hydrolase, family IB" amino acids 85 to 254 (170 residues), 110.3 bits, see alignment E=1e-35 PF12710: HAD" amino acids 87 to 254 (168 residues), 72.2 bits, see alignment E=1.2e-23 PF08282: Hydrolase_3" amino acids 223 to 276 (54 residues), 32.6 bits, see alignment E=1e-11

Best Hits

KEGG orthology group: K01079, phosphoserine phosphatase [EC: 3.1.3.3] (inferred from 81% identity to xau:Xaut_1660)

Predicted SEED Role

"Phosphoserine phosphatase (EC 3.1.3.3)" in subsystem Glycine and Serine Utilization or Serine Biosynthesis (EC 3.1.3.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.3.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (299 amino acids)

>GFF259 hypothetical protein (Xanthobacter sp. DMC5)
MAYVATLISNPSAPALTYEAIHAALSVLPEAQDPVVLDEGVAVDIHFAPELAADAGALTD
AVRGVLNGAPIDVVVQLETGRRKRLFLADMDSTMIGQECIDELADLVGLKAHVSAITERA
MRGEIAFEPALRERVALLRGLSASVVGDVLRERITLTPGGPELVGTMKANGAYAALVSGG
FTLFTQEIAARIGFDEHRANELLVEAGTLVGSVAEPILGREAKLATLVDLRDQLHLAPSE
TMAVGDGANDLAMLGEAGLGVAYHAKPAVAAAAHARVDHGDLTALLYMQGYSRSEFRIA