Protein Info for GFF2578 in Xanthobacter sp. DMC5

Annotation: Solute-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 349 signal peptide" amino acids 1 to 37 (37 residues), see Phobius details PF03480: DctP" amino acids 61 to 323 (263 residues), 130 bits, see alignment E=5.7e-42

Best Hits

Swiss-Prot: 66% identical to DCTP_RHOFT: Solute-binding protein Rfer_1840 (Rfer_1840) from Rhodoferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118)

KEGG orthology group: None (inferred from 80% identity to azc:AZC_3299)

Predicted SEED Role

"TRAP transporter solute receptor, unknown substrate 4"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (349 amino acids)

>GFF2578 Solute-binding protein (Xanthobacter sp. DMC5)
MSHDHSLIHRPVSRRLVLAGALAAPALLRFTGTAHAATTLKISHQFPSSSGEEGDFRDRL
VRRFAEEVTKRTNGELAFEIYPGSSLMKTNAQFSALRKGALDLSLYPISYAGGEAPECNI
GLMPGLVVSYDQGLAWRTKPVGQAFSEYLESKGVKILTWVWQAGGVASREKPLIAPEDAK
GMKIRGGSREMDMVLQAAGAAVLSLPSNELYVAMQTGACDAGITSSTSLISFRLEELAKQ
LTTGRGKSYWFMLEPLLISKAVFDKLPKAQQDVLSAVGLEMEAFGKAGAMADDTKVAEVF
AKAGAKIHDLDVATVEKWRAIARDTAWKDYSAKSAGCANLMKLAQEVPA