Protein Info for GFF2573 in Xanthobacter sp. DMC5

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1141 PF08379: Bact_transglu_N" amino acids 7 to 81 (75 residues), 88.3 bits, see alignment 6.8e-29 PF01841: Transglut_core" amino acids 143 to 246 (104 residues), 55.9 bits, see alignment E=7.2e-19 PF09899: DUF2126" amino acids 277 to 1136 (860 residues), 1324.3 bits, see alignment E=0

Best Hits

Predicted SEED Role

"Large protein containing transglutaminase-like domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1141 amino acids)

>GFF2573 hypothetical protein (Xanthobacter sp. DMC5)
MSILASLHHVTSYTYDHPVSMGPQVIRLRPAPHSRTDIPAYSLKISPADHFINWQQDPFG
NWLARIVFPERVTEFKVEVDLLAKLDVINPFDFFVEEYAESFPFEYAPALKAELAPYLEL
EDEGALFADYLASVPREKTRIVDFLVYLNQRLQSEVGYVIRMEPGVQTPDETLTRKLGSC
RDTGWLLVQLLRHLGLAARFVSGYLIQLKPDVAALDGPSGTDVDFTDLHAWCEVFVPGAG
WIGLDPTSGLLCGEGHIPLAATPHYSSAAPISGYVNEKAEVEFGFDMQVVRVAEAPRVTL
PFSDETWAALDQLGHKVDEDLKAGDVRLTMGGEPTFVSIDDYQSPEWNTEALGPHKRERA
DDLIRRLRRRFETEGVLHYGQGKWYPGETLPRWSFDLFWRKDGQPIWQREDLIADEKVNY
GVTPADAERFCKAVAEKLAVGSEFVQQAFEDNIYYMWKEQNLPENIAPGDPRMADEVQRR
MLARTFNQGLGTATGSVLPLRRVWTPTGPAWRSEEWTYRRQFLFLIPGESPMGYRLPLES
LHYLAPTRYPYIVEADPFEPRAPLPDAADFSARYSAGQGGVGAGTDGSNAGTPGGPGGMP
RHSIAPRTEAYGVGERAQELAREYLAKYDTQIFTADTRTALCVEPRNGRLCVFLPPVEIL
EDYLDLVAALEQVAIELNTPIHMEGYPPPFDYRLNLIRIAPDPGVLEVNVHPSASWAGCV
EITRILYEEARLARLGTEKFMVDGRHTGTGGGNHVVVGGSTPADSPFLRRPDVLKSLLLY
WQRHPCLSYFFSGLFIGPTSQHPRVDEARHDSLYELEIAFSKFPAPGQGEPPAPWLVDRL
LRNLLVDVTGNTHRTEISIDKLYSPDGPTGRLGLVEFRCFEMPPDWRMSLAQQLLLRALI
ARLWNKPVHGHCTRWGTILNDRFMLPHYVWQDFLDVVEDLSDAGYQIDPEWFRAQFEFRF
PAFGKVQQAGVDIEVRQALECWHVLGEEGVVGGTARYVDSSVERLQVKVEGFNPSRHILT
CNGRKVPLAPTGRNGTYVAGVRYKAWQPWSGLHPTIPVHSPLTFDLVDTWSERSRGGCMY
YVSHPGGRNYDTFPVNSYEAEARRLARFQTFGHTPGTLDVVLETAPDEFPTTLDLRRPAS
A