Protein Info for GFF2512 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Exported zinc metalloprotease YfgC precursor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 563 signal peptide" amino acids 1 to 37 (37 residues), see Phobius details transmembrane" amino acids 128 to 146 (19 residues), see Phobius details amino acids 178 to 195 (18 residues), see Phobius details amino acids 229 to 248 (20 residues), see Phobius details PF01435: Peptidase_M48" amino acids 114 to 281 (168 residues), 101.6 bits, see alignment E=2.5e-33

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (563 amino acids)

>GFF2512 Exported zinc metalloprotease YfgC precursor (Hydrogenophaga sp. GW460-11-11-14-LB1)
MRFFLKSLLPPVPRSALALGLLAVASMLLPVPASIAQPVRDSTSTSSLPSLGDGGGMSIS
AERRLGDRIARDIYRDPDYLDDPVLGDYLQALWQPLLGAARDRGDVPPELAERMAWELVV
SRDKRVNAFALPGGYLGVNLGLMALTDKPEELASVMAHELSHVSQRHISRMMAREERMAP
WMMAAMILGALAAGSNPQVATAAIAGSSAVAAQTQLNFSRDMEREADRVGFGVLTGAGFD
GLGFVTMFDKMQQSSRYDDGSFPYLRSHPLTGERMADMRSRIPSGPVAAAGGQMGPVSAA
VPVAAVPSASPGLRLDLPGSRGASHSAVGLPMPSRNVHALVSARAKVLAENGPDRQRAWL
TNGRAANASPGDRYAAALSALRLGQRDLALELAQSLRTAVAPEARPTVDALLLDILLSPV
AGGVPSLPPAQATLLAELRDQALGGTSRASALLGAQAALATGQAQRAVSRLQTWVAQQPR
DAVAWQTLSRAYAVQGQTLRSIRAEAEARAAHLDFGGAVDRFKAAQALPAAQRTDGMELA
IVDSRRREVEAQLRESVREESER