Protein Info for GFF2509 in Variovorax sp. SCN45

Annotation: Type IV fimbrial assembly protein PilC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 409 transmembrane" amino acids 175 to 199 (25 residues), see Phobius details amino acids 220 to 221 (2 residues), see Phobius details amino acids 224 to 244 (21 residues), see Phobius details amino acids 381 to 402 (22 residues), see Phobius details PF00482: T2SSF" amino acids 75 to 198 (124 residues), 119 bits, see alignment E=6.3e-39 amino acids 279 to 401 (123 residues), 105.5 bits, see alignment E=9.7e-35

Best Hits

Swiss-Prot: 52% identical to TAPC_AERHY: Type IV pilus assembly protein TapC (tapC) from Aeromonas hydrophila

KEGG orthology group: K02653, type IV pilus assembly protein PilC (inferred from 94% identity to vpe:Varpa_4833)

Predicted SEED Role

"Type IV fimbrial assembly protein PilC" in subsystem Type IV pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (409 amino acids)

>GFF2509 Type IV fimbrial assembly protein PilC (Variovorax sp. SCN45)
MATVASSRSQPTHKEFVFEWEGKDRNGKLVRGELRAAGENQVQAALRRQGVLASKIKKRR
MRSGKKIKPKDIAIFTRQLATMMKAGVPLMQSFDIVGRGNANASVAKLLNDIRSDVETGT
SLSMAFRKFPKYFDNLYCNLVEAGEAAGILEELLDRLATYMEKTEAIKSKIKSALMYPTS
VIVVAFVVVAIIMIFVIPAFKQVFTSFGADLPAPTLFVMAISEFFVSYWWLIFGGLGGGI
YFFLQAWKRNERVQRVMDRALLRVPIFGVLIEKSCVARWTRTLATMFAAGIPLVEALDSV
GGASGNTVYGDATAKIQQEVSTGTSLTAAMTNVNLFPSMVIQMTAIGEESGSIDHMLGKA
ADFYESEVDDMVAGLSSLMEPIIIVFLGTIIGGIVVSMYLPIFKLGQVV