Protein Info for GFF2502 in Xanthobacter sp. DMC5

Annotation: ATP synthase subunit a

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 transmembrane" amino acids 26 to 48 (23 residues), see Phobius details amino acids 83 to 107 (25 residues), see Phobius details amino acids 113 to 135 (23 residues), see Phobius details amino acids 142 to 166 (25 residues), see Phobius details amino acids 186 to 207 (22 residues), see Phobius details amino acids 213 to 241 (29 residues), see Phobius details TIGR01131: ATP synthase F0, A subunit" amino acids 6 to 246 (241 residues), 227.9 bits, see alignment E=7.6e-72 PF00119: ATP-synt_A" amino acids 32 to 243 (212 residues), 215.5 bits, see alignment E=4.4e-68

Best Hits

Swiss-Prot: 93% identical to ATP6_XANP2: ATP synthase subunit a (atpB) from Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2)

KEGG orthology group: K02108, F-type H+-transporting ATPase subunit a [EC: 3.6.3.14] (inferred from 93% identity to xau:Xaut_1979)

Predicted SEED Role

"ATP synthase F0 sector subunit a"

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.14

Use Curated BLAST to search for 3.6.3.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (250 amino acids)

>GFF2502 ATP synthase subunit a (Xanthobacter sp. DMC5)
MTVDPIHQFEIKRYVDLLNLSSVQFSFTNAAVFMFGIVAIIFFFLTYATRGRTLVPGRAQ
SAAEMSYEFIAKMVRDSAGNQGMVFFPLVFSLFMFVLVANVVGLIPYTFTVTAHLIVTAA
LALLVIGTVIIYGFVKHGTHFLHLFVPSGVPGFLLPFLVVIEVVSFLSRPISLSLRLFAN
MLAGHIALKVFAFFVVGLASAGVAGWFGATLPFLMIVALTALELLVAVLQAYVFAVLTSI
YLNDAIHPGH