Protein Info for PS417_01265 in Pseudomonas simiae WCS417

Annotation: CbbBc protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01701: oxidoreductase alpha (molybdopterin) subunit
  • amino acids 22 to 770 (749 residues), 948.1 bits, E=1.6e-289
• PF00384: Molybdopterin
  • amino acids 118 to 499 (382 residues), 85.9 bits, E=1.5e-28

Best Hits

KEGG orthology group: K00123, formate dehydrogenase, alpha subunit [EC: 1.2.1.2] (inferred from 98% identity to pfs:PFLU0278)

Predicted SEED Role

"Putative formate dehydrogenase oxidoreductase protein" in subsystem Formate hydrogenase

MetaCyc Pathways

• formate oxidation to CO₂ (1/1 steps found)
• purine nucleobases degradation II (anaerobic) (16/24 steps found)
• oxalate degradation VI (1/4 steps found)
• oxalate degradation III (1/5 steps found)
• superpathway of C1 compounds oxidation to CO₂ (5/12 steps found)
• purine nucleobases degradation I (anaerobic) (6/15 steps found)

KEGG Metabolic Maps

• Glyoxylate and dicarboxylate metabolism
• Methane metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.2.1.2

Use Curated BLAST to search for 1.2.1.2

Sequence Analysis Tools

See A0A1N7UBA4 at UniProt or InterPro

Protein Sequence (782 amino acids)

>PS417_01265 CbbBc protein (Pseudomonas simiae WCS417)
MSQHHQADQTPTPRYKPYKGPAGGWGALISVAQAWLTSDNALKNLRMMLKTNQNGGFDCP
GCAWGDSPESGMVKFCENGAKAVNWEATKRRVDGAFFAKNSVTALLEQSDYWLEYQGRLT
EPMRYDAETDRYKPISWEAAFDLVGKHLNALPSPDMAEFYTSGRASNEAAYLYQLFVRAY
GTNNFPDCSNMCHEASGVALAQSVGVGKGTVTFDDFEHADAIFVWGQNPGTNHPRMLEPL
REAVKRGAQVVCINPLKERGLERFQHPQHPLEMLTNGDKPTNTAYFRPALGGDMAILRGM
AKFLLLWERQAQAEGKEAVFDHDFLNEHTTNVLDYLGKIDDTSWEEIVEQSGLTLVEIEQ
AARMYAKGKNVIMCWAMGITQHRHSVPTIQEIANLMLLRGNIGRPGAGLCPVRGHSNVQG
DRTMGINERPPVAFLDALERRFQFQVPRVNGHNVVEAIHAMLEGRAKVFIGLGGNFAQAT
PDSPRTFEALRNCDLTVQISTKLNRSHLMHGKDALILPCLGRTDIDIQAEGPQAVTVEDS
FSMVHGSNGQLQPLSKLMKSEPAILAGIAAATLGTKPVDWNWLVADYSRIRDLIADTIPG
FKDFNEKIKHPGGFYLGNSAGARRWNTPSGRASFRPNILPKDLIHERTHATGKVPDLIMQ
SMRSHDQYNTTIYGLDDRYRGVKGQRDVLFVNEADIIRLGFKPGQKADIVSLWEDGRERR
VKGFTLLAFDIPAGQAAAYYPEVNPLVPLESTGDGSHTPTSKFVAIRLEAASDNGLIMAR
SA