Protein Info for GFF2479 in Hydrogenophaga sp. GW460-11-11-14-LB1
Annotation: ABC-type hemin transport system, ATPase component
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 44% identical to HMUV_BURL3: Hemin import ATP-binding protein HmuV (hmuV) from Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)
KEGG orthology group: K02013, iron complex transport system ATP-binding protein [EC: 3.6.3.34] (inferred from 54% identity to vpe:Varpa_2075)Predicted SEED Role
No annotation
Isozymes
Compare fitness of predicted isozymes for: 3.6.3.34
Use Curated BLAST to search for 3.6.3.34
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (315 amino acids)
>GFF2479 ABC-type hemin transport system, ATPase component (Hydrogenophaga sp. GW460-11-11-14-LB1) VNARLLDADWRCACGELPAGERPLWLDDDDDDPVTDAPALDDGQGLCALDVGVRAGASTL LQGVQLRLAPGEVGAILGPNGAGKSTLLSVLSGLRAPDTGRVTLNGLAVTPATVHQLARH RAVLPQETAVAFDFRVQDVVELGRYPHHLQPSPHEAAIVRAAMQATGVADMADRSVSSLS GGERARAQLARVMAQIWEPLADGAPRWLLLDEPTASLDLRHQHETLGTVQRWAREQGVGV LAVLHDPNLALRYADRAWVLDGGVLQASGPPARVLRPALVQRVWQVQASTVRAADGVPQL LIAAGVPPTTGKERP