Protein Info for GFF2477 in Variovorax sp. SCN45

Annotation: Tripartite tricarboxylate transporter TctA family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 503 transmembrane" amino acids 20 to 43 (24 residues), see Phobius details amino acids 45 to 71 (27 residues), see Phobius details amino acids 109 to 132 (24 residues), see Phobius details amino acids 148 to 183 (36 residues), see Phobius details amino acids 203 to 224 (22 residues), see Phobius details amino acids 259 to 280 (22 residues), see Phobius details amino acids 319 to 342 (24 residues), see Phobius details amino acids 357 to 379 (23 residues), see Phobius details amino acids 390 to 408 (19 residues), see Phobius details amino acids 414 to 430 (17 residues), see Phobius details amino acids 437 to 456 (20 residues), see Phobius details amino acids 469 to 490 (22 residues), see Phobius details PF01970: TctA" amino acids 20 to 441 (422 residues), 523.6 bits, see alignment E=1.6e-161

Best Hits

Swiss-Prot: 62% identical to YZ2R_AGRVI: Uncharacterized 52.8 kDa protein in TAR-I ttuC' 3'region from Agrobacterium vitis

KEGG orthology group: None (inferred from 90% identity to vap:Vapar_0317)

Predicted SEED Role

"Tricarboxylate transport membrane protein TctA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (503 amino acids)

>GFF2477 Tripartite tricarboxylate transporter TctA family (Variovorax sp. SCN45)
MDLITNLSIGFGVAFTAQNLVYAFVGCLLGTLIGVLPGIGPVATIAMLLPATYALPPVSA
LIMLAGIYYGAQYGGSTTAILVNLPGESSSVVTVIDGYQMARKGRAGPALAAAGLGSFFA
GCVGTLILAAFAPPLTELAFKFGPAEYFSLMILGLIGAVVLASGSLLKAITMILLGLALG
LVGTDVNSGVARYSFDIPELTDGIGFIAIAMGVFGYGEIIANLAVPEHEREVFTAKVKGL
WPTKQDFKDMTPAVLRGTALGSALGILPGGGALLSAFAAYTIEKKIKLKQGEIAFGKGNI
RGVAGPESANNAGAQTSFIPLLTLGIPPNAVMALMVGAMTIHNIQPGPQVMTSNPELFWG
LIASMWIGNLMLIVLNLPMIGIWIKLLTIPYKWLFPSIVLFCAVGVYSENNNTFDVWMVA
IFGIVGYLFLKLKCEPAPLLLGFILGPMMEENLRRALLLSRGDWSVFVTRPLSAGLLIAA
ALLLVLVLLPSVKAKREEAFVED