Protein Info for GFF2475 in Sphingobium sp. HT1-2

Annotation: FIG000875: Thioredoxin domain-containing protein EC-YbbN

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 303 PF00085: Thioredoxin" amino acids 13 to 112 (100 residues), 89.3 bits, see alignment E=5.5e-29 PF00578: AhpC-TSA" amino acids 28 to 77 (50 residues), 27.4 bits, see alignment 1e-09 PF13905: Thioredoxin_8" amino acids 29 to 71 (43 residues), 29.7 bits, see alignment 2.4e-10 PF13429: TPR_15" amino acids 110 to 255 (146 residues), 27.7 bits, see alignment E=6.6e-10 PF14559: TPR_19" amino acids 142 to 208 (67 residues), 46 bits, see alignment E=1.9e-15 PF14561: TPR_20" amino acids 216 to 302 (87 residues), 101.1 bits, see alignment E=1.2e-32

Best Hits

KEGG orthology group: K05838, putative thioredoxin (inferred from 86% identity to sjp:SJA_C1-28940)

Predicted SEED Role

"FIG000875: Thioredoxin domain-containing protein EC-YbbN"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (303 amino acids)

>GFF2475 FIG000875: Thioredoxin domain-containing protein EC-YbbN (Sphingobium sp. HT1-2)
VATLGLSEADKAAVEAFRQDVVEPSRTSLVIVDFWAEWCGPCKQLAPVIEKVCADYASKG
VKLVKVNVDENGFIASQFRVQSIPTVYAVFQGQPVADLSQARTEGQLKQYLDQLLSQLPI
ESDEKAQAQEIAPLIAMGEEMLAGGEAERALSVFQQIADIAPDNAEVLSGLLRALVALGQ
LDEADALLAELPAEMQKDQAIERAKAALALARNAKPVADLSGVEARLAADADDHAARFEL
ATGLMGNGDRDGAAEQLLEIVRRDRAWNDGAARTQLLTLFEAVGLEDPWVSAQRRKLSQI
LFS