Protein Info for GFF2466 in Xanthobacter sp. DMC5

Annotation: lipid kinase YegS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 318 PF00781: DAGK_cat" amino acids 11 to 128 (118 residues), 78.9 bits, see alignment E=2.5e-26 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family" amino acids 53 to 296 (244 residues), 147.4 bits, see alignment E=2.3e-47 PF19279: YegS_C" amino acids 138 to 292 (155 residues), 84.8 bits, see alignment E=5.6e-28

Best Hits

KEGG orthology group: K07029, (no description) (inferred from 77% identity to xau:Xaut_1943)

Predicted SEED Role

"Transcription regulator [contains diacylglycerol kinase catalytic domain]"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (318 amino acids)

>GFF2466 lipid kinase YegS (Xanthobacter sp. DMC5)
MTAQGPKSRRRALFMVNPRARGGSLPLEAVRAVLETEFDLLETPLPSPGELSDLLRARAD
EVDIVILGGGDGTLNAAASGLYDTQLPLGVLPLGTANDFARTLAIPTDPLAAARVILAHP
PRFIDLGDVNGHPFLNVASIGFSADLARALTREAKRYFGVVGYGIVAARLLIQSRLFTAY
IEHDGTAEAVRTLQVSVGNGRHYGGGMTVEASATADDGQLDFYSLEVDHWWRLLALLPSL
RAGTQGQWDDVRAFRTKKVVVRTSRPRPVNTDGELVTYTPAHFSIRPAAIRVHAPPQTVT
RSGSGEQNSLQPLAEGTP