Protein Info for GFF2422 in Xanthobacter sp. DMC5

Annotation: Ferrichrome outer membrane transporter/phage receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 831 signal peptide" amino acids 1 to 42 (42 residues), see Phobius details PF07660: STN" amino acids 72 to 120 (49 residues), 37.8 bits, see alignment 2e-13 PF07715: Plug" amino acids 162 to 265 (104 residues), 83.3 bits, see alignment E=2.6e-27 TIGR01783: TonB-dependent siderophore receptor" amino acids 164 to 830 (667 residues), 383.9 bits, see alignment E=8.4e-119 PF00593: TonB_dep_Rec_b-barrel" amino acids 338 to 800 (463 residues), 203.7 bits, see alignment E=1.5e-63

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 71% identity to azc:AZC_4433)

Predicted SEED Role

"Ferrichrome-iron receptor" in subsystem Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (831 amino acids)

>GFF2422 Ferrichrome outer membrane transporter/phage receptor (Xanthobacter sp. DMC5)
MAAGWERLRRRADGTAGRTAWLSGTAVCALLAIACPGAAHAQEGAPGIAFSIPAQDLGSA
LTRFADTADLRLLFPSDLVAGRRTSGLSGTYSRDAGLARLLAGTGLVYRFTSANTVTITS
PQAQGAAGSGADWLGTVDVEGDNTQQVVALETSAGTKTETPLIDTPQSISVVTRAEMDQR
GVQDFNSAVAYTPGVRAVDYPGGQGMPDIYIRGFRAIDQNANYRDGLRNGFNNYDSDIEV
YGLQRLDVVKGPTSALYGAGTPGGIIDAVTKRPTATPLHEIEILGGNYDRIQGAFDIGGP
ATEDGTWLYRLTGLFRDSGTQIDYSPDNRIYIAPAVTWQPNANTSLTLLANYQKTEKGGS
EQSIPMANSLFQLGPKISPSLYLGAPGLSSWNVENTSVGYEFKHRFENDWQLVQNARYTH
SDVDYASAWGWDWPIAVVDNKYFNVGVQLRPKVSDSFLIDTHLSRDFQTGPVAHKILLGV
DGGWYNASEVRTNSTNYNSINIFAPDYNFIYTFGRPWSDTESTISQIGVYAQDQMTLNNW
LLTLSGRQDWARNEEANYYSRTILADYGFTDEVVAANYSAFTWRAGLGYKFDNGVMPYAS
YATSFLPVAGTDFQGRSFKPTTGEQYEAGIKYEPQGWRAMFTASVFQITQQNVLTTDPVN
VGYSVQDGEVRSRGIELEAKANVTANLDIIASYTYLDTVVTQDNANDAGISKVGTTPSSV
PHNSAALWAYYTFHGGTLDGLGIGAGLRYVGSSWAVMNDANGGQIAIPGYTLVDASLRYD
LGKLDQRLRGATFSLSGTNIFDTEYYTAGFYWNSVIYGTRRTVYASLNYRW