Protein Info for GFF2405 in Variovorax sp. SCN45

Annotation: Peptide-methionine (R)-S-oxide reductase MsrB (EC 1.8.4.12)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 169 signal peptide" amino acids 1 to 35 (35 residues), see Phobius details TIGR00357: methionine-R-sulfoxide reductase" amino acids 44 to 167 (124 residues), 164.2 bits, see alignment E=8e-53 PF01641: SelR" amino acids 53 to 166 (114 residues), 162.2 bits, see alignment E=2.2e-52

Best Hits

KEGG orthology group: K07305, peptide-methionine (R)-S-oxide reductase [EC: 1.8.4.12] (inferred from 68% identity to rpx:Rpdx1_1413)

Predicted SEED Role

"Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12)" (EC 1.8.4.12)

Isozymes

Compare fitness of predicted isozymes for: 1.8.4.12

Use Curated BLAST to search for 1.8.4.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (169 amino acids)

>GFF2405 Peptide-methionine (R)-S-oxide reductase MsrB (EC 1.8.4.12) (Variovorax sp. SCN45)
MNHHGRRFILKAGSSTLGLALFNGFGWSAGLAHAAEPGKFEITRTDAEWRKLLTPNQYAV
LRQEGTERPYSSPLNDEHREGRFACAGCSLEAFSSKTKFDSKTGWPSFWQPLPNAVGQKG
DTSGGMTRTEVHCSRCGGHLGHVFDDGPKPTGLRYCMNGLAMKFNPGAA