Protein Info for GFF24 in Hydrogenophaga sp. GW460-11-11-14-LB1
Annotation: Hydroxymethylpyrimidine ABC transporter, transmembrane component
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K02050, sulfonate/nitrate/taurine transport system permease protein (inferred from 32% identity to rop:ROP_50120)Predicted SEED Role
No annotation
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (252 amino acids)
>GFF24 Hydroxymethylpyrimidine ABC transporter, transmembrane component (Hydrogenophaga sp. GW460-11-11-14-LB1) MRLDRSHLTKAAGVVLFLAAWQAGATLGNTRMLPGIPDVARQLAEMIQSGELFEHALSTL SKGFLGLALALVAGAAVGILCARHRYTDAALHPVISMLYPVPKLALYPVVVLIFGFGGAS KIVQVGLECFFPIFVQMYAGTRAVPRNLLWLAENNEVGPLRMVRDVLLPSLLPYLLTGLR VATPIMLIVMCVTEFIGESKGLGYLISRYSSYFDTASAFAVIVVLGLFGLVADRLIVYLR TRAVFWERGVSL