Protein Info for GFF2390 in Sphingobium sp. HT1-2

Annotation: Uncharacterized membrane protein PA1577

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 112 signal peptide" amino acids 1 to 15 (15 residues), see Phobius details transmembrane" amino acids 30 to 49 (20 residues), see Phobius details amino acids 67 to 85 (19 residues), see Phobius details amino acids 91 to 110 (20 residues), see Phobius details PF04342: DMT_6" amino acids 3 to 108 (106 residues), 140.1 bits, see alignment E=1.5e-45

Best Hits

KEGG orthology group: K09922, hypothetical protein (inferred from 88% identity to sjp:SJA_C1-23880)

Predicted SEED Role

"protein of unknown function DUF486"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (112 amino acids)

>GFF2390 Uncharacterized membrane protein PA1577 (Sphingobium sp. HT1-2)
MPTIILLILSNLFMTTAWYWHLKGGMNKPLMLVILISWAIAFVEYCLAVPANRIGFAHGW
SAGQLKIAQEAIALVIFGIFMVTVLGEPLHWRHAAAFACIMAAVGFLFVGRS