Protein Info for PS417_12180 in Pseudomonas simiae WCS417

Annotation: ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 619 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF00496: SBP_bac_5" amino acids 104 to 512 (409 residues), 223 bits, see alignment E=3.3e-70

Best Hits

KEGG orthology group: K13893, microcin C transport system substrate-binding protein (inferred from 99% identity to pfs:PFLU2634)

Predicted SEED Role

"ABC transporter, periplasmic substrate-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UH45 at UniProt or InterPro

Protein Sequence (619 amino acids)

>PS417_12180 ABC transporter substrate-binding protein (Pseudomonas simiae WCS417)
MRLAFSYIFSSTLALLLASSVVIAAPQPYLTVYGEPAKYAAGFTHFDYANPNAPKGGSLR
RSAIEIGRFDHVLPYIDKGIGVSQVDGWLYAPLAQRSLDEPYTVYGLVAEKMERADDGLS
LRFFLNPKARFADGKPITAEDVRYSFDLLMTQGSLRFRTLFADVKHVEVEGERQVRFDFS
SNENRTLPLDIATLPVFPEHWWKTRDFANGGGYEAPLGSGPYKVSKIDSGSTITFTRDPN
WWGKDLPVSRGLYNFDHLSLEYFGDTEVARQVLRGGAYDFNREFSATGYSIGYNGPALDD
GRLQRAHLAKEMPQPAQGYVFNVQKPVFKDRRVRQALAMLWDFEWANRQMMRNMYIRQQS
FFSNSPLAATQPPTQEELAILEPLRGQVPDEVFTQVFKAPVTDGSGMIRDKQLQALALLE
EAGWKPHGDKLVNAEGEPLEFTFLNAQSGLERLLLPYKRNLAQIGITLNIRRIDASQYVN
RVMARDYDMIVTGFPVTTSPGMELYNYFGSAAAFDPGANNYMVLKDPAVDSLIKGLVKAD
TQAQMLTYAHALDRVLQWNYLWIPNYYPPGTSAAWWNRFGRPAIEAKNDEALETWWEISP
TPLTNEQMNAELKKRGGAR