Protein Info for GFF2341 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: UPF0141 membrane protein YijP possibly required for phosphoethanolamine modification of lipopolysaccharide

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 577 transmembrane" amino acids 16 to 38 (23 residues), see Phobius details amino acids 49 to 64 (16 residues), see Phobius details amino acids 70 to 91 (22 residues), see Phobius details amino acids 119 to 139 (21 residues), see Phobius details amino acids 151 to 172 (22 residues), see Phobius details PF00884: Sulfatase" amino acids 237 to 529 (293 residues), 189.8 bits, see alignment E=3.7e-60

Best Hits

Swiss-Prot: 100% identical to CPTA_SALTY: Phosphoethanolamine transferase CptA (cptA) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: None (inferred from 100% identity to sty:STY3755)

MetaCyc: 89% identical to phosphoethanolamine transferase EptC (Escherichia coli K-12 substr. MG1655)
2.7.8.M9 [EC: 2.7.8.M9]

Predicted SEED Role

"UPF0141 membrane protein YijP possibly required for phosphoethanolamine modification of lipopolysaccharide" in subsystem Lipid A modifications

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.8.M9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (577 amino acids)

>GFF2341 UPF0141 membrane protein YijP possibly required for phosphoethanolamine modification of lipopolysaccharide (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MQSTLLQTKPAFSWKALGWALLYFWFFSTLLQAIIYLTGYSGTNGLRDSLLYSSLWLIPV
FLFPGRIRVIAAVIGVVLWAASLAALSYYVIYGQEFSQSVLFVMFETNANEASEYLSQYF
SLKIVLVALAYTVAAILLWTRLRPVYIPSPWRYLVSFALLYGLILHPIAMNTFIKHKSME
KTLDSLASRMEPAAPWQFITGYYQYRLQLASLNKLLNENDALPPLANFQDHSGDAPRTLV
LVIGESTQRGRMSLYGYPRETTPELDALHKTDPGLTVFNNVVTSRPYTIEILQQALTFAD
EKNPDWYLTKPSLMNMMKQAGYKTFWITNQQTMTARNTMLTVFSKQTDKQFYMNQQRTQS
AREYDSNVLAPFKAVLADPAPKKFIIVHLLGTHIKYKFRYPENQGKFDGKTDHVPPGLSS
DELESYNDYDNANLYNDYVVASLIKDYKATDPNGFLLYFSDHGEEVYDTPPHKTQGRNED
SPTRHMYTVPFLLWTSEKWQAAHPRDFSQDVDRKYSSSELIHTWSDLAGLTYDGYDPTRS
ITNPQFKETTRWIGNPYKKNALIDYDTLPYGDQVGNQ