Protein Info for GFF2316 in Xanthobacter sp. DMC5

Annotation: Sensor histidine kinase RcsC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 958 transmembrane" amino acids 22 to 47 (26 residues), see Phobius details amino acids 57 to 85 (29 residues), see Phobius details amino acids 98 to 120 (23 residues), see Phobius details TIGR00229: PAS domain S-box protein" amino acids 147 to 268 (122 residues), 38.2 bits, see alignment E=7.2e-14 amino acids 271 to 395 (125 residues), 47.5 bits, see alignment E=9.6e-17 PF13188: PAS_8" amino acids 148 to 195 (48 residues), 15.2 bits, see alignment 6.6e-06 PF08448: PAS_4" amino acids 153 to 264 (112 residues), 68 bits, see alignment E=3.3e-22 amino acids 281 to 387 (107 residues), 41.8 bits, see alignment E=4.6e-14 PF13426: PAS_9" amino acids 157 to 261 (105 residues), 18 bits, see alignment E=1.1e-06 amino acids 286 to 387 (102 residues), 28.8 bits, see alignment E=5e-10 PF00989: PAS" amino acids 275 to 385 (111 residues), 23 bits, see alignment E=2.7e-08 PF08447: PAS_3" amino acids 298 to 380 (83 residues), 66.5 bits, see alignment E=8.2e-22 PF02518: HATPase_c" amino acids 561 to 681 (121 residues), 57.4 bits, see alignment E=7.4e-19 PF00072: Response_reg" amino acids 707 to 818 (112 residues), 54.8 bits, see alignment E=4.1e-18 amino acids 831 to 947 (117 residues), 59.6 bits, see alignment E=1.3e-19

Best Hits

KEGG orthology group: None (inferred from 72% identity to xau:Xaut_2026)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (958 amino acids)

>GFF2316 Sensor histidine kinase RcsC (Xanthobacter sp. DMC5)
MDLSSRGPAGLFLRIIAEPRPLWWRFAFAGTVVGAALVLRLGLIAWMVEFPPYLLQLPAI
IVVALVCGAECGLAAIAVLVGVNAALLPEGPDGGVAPSALASLLSFTVNSFAVWAIAGLV
RTTLRRLDSAHAALLSAASEQTAVVATLEALLQHAPVGFAFFDAQRRFIRVNEMLARIDG
IPAREHAGRSLADMLPQLADAVTPSLERVLATGEVIADVELEGATPAAPGVWRHFLVSYF
PVRTSSEAINLVGMIVVEITERKRAEKAIAASEQRYRLLAEALPKMVWTSSPAGTGDYYN
HRWAEYTGVEAPPGEVVEWHAFLHPEEKGGIMGAWEASLASGNPFSRECRFRAKDGSYRW
FLCRAVPVRDEDGRVDRWYGSCTDISEIVAAREALSRTNEDLERLAAARTMQLAETNTLL
KQEMEERLRAESQLRQAQKMEAVGQLTGGIAHDFNNLLTIIIGNIEAAERRVPADPQDTR
TQEIKTQEIRRFLDYGRQGALRAAILTQRLLAFSRRQPLDPRPTDVNRLVTGMSHMLRSA
LGERVMVETVLAGGLWRTEIDHNQLENAILNLAVNARDAMMDGGKLTIETANAYLDEAYC
AEHEDLEPGQYVAIFVSDTGMGMSDDVRARAFEPFFTTKGPKDGTGLGLSQVYGFVKQSG
GHVMIYSERGDGTTVKLYLPRLEETPSVPEPDPPRTDGETRAAPAVVLMVEDDDQLRTMG
AATLREAGHTVIEAEDASAALDALSRGARPDLLFTDVRLGDGMDGRGLADEVKRRLPRTR
VLFTTAYARNAVVHQGRLDPGMKLLTKPYSQSELVTKVNGMLDEPALRGAVLLVEDEPFV
AMVASQILEDQGFKVTVASHGEAALSHARNAKADIGRDALVLAIVDIGLPDMRGDEVVRR
LGEIAPELPVIVATGYATQDISQMFGGRVDVGVISKPYDGATLVAALERVGFRPKGEG