Protein Info for PS417_11760 in Pseudomonas simiae WCS417

Annotation: Fis family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 621 PF01590: GAF" amino acids 83 to 207 (125 residues), 38.7 bits, see alignment E=2.8e-13 PF00158: Sigma54_activat" amino acids 320 to 478 (159 residues), 210.4 bits, see alignment E=2.9e-66 PF14532: Sigma54_activ_2" amino acids 332 to 487 (156 residues), 69.3 bits, see alignment E=8.7e-23 PF02954: HTH_8" amino acids 575 to 610 (36 residues), 22.4 bits, see alignment 1.7e-08

Best Hits

KEGG orthology group: None (inferred from 72% identity to pae:PA4147)

Predicted SEED Role

"Transcriptional activator of acetoin dehydrogenase operon AcoR" in subsystem Acetoin, butanediol metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7TX15 at UniProt or InterPro

Protein Sequence (621 amino acids)

>PS417_11760 Fis family transcriptional regulator (Pseudomonas simiae WCS417)
MLAAHSREHVDCVSRVVRNADRLPQAPVPSLIFDSWRRSMEQHHLDPGSLQGPRILSEPL
LRECRERADLFMRIASEEVGQLHHRVRHADYCVMLTDAQGQTIDHRVDTSIRNDCRKAGL
YLGTCWSEAEEGTCGVATVLTSQSAVTVHKRDHFRAAFIGLTCSAAPIFDPQGNLLGVMD
ASALKSPDDRRSQHLVRQMVAQSAQAIENAFFMHSARQHWVLQAHSTPGYVDSQPDLLLA
WDQDGRLHALNSKARQALRRRFGQVPEHIGDVFDLDALRAVTHDATQQLPWLGEPGVLHV
RVNAPRRKPARAAVIPLVDARVEEHLRLALRVKNRNLPVLVQGETGAGKEVFARQLHERS
ARHTGPFVAVNCAAIPENLIESELFGYVAGAFTGASSKGMPGLLVQADGGTLFLDEIGDM
PLALQTRLLRVMAEGEVAPLGAAKTRAVDIHVICASHRDLSVLVSEGRFREDLFFRLGCA
RFCLPPLRERTDKLALINRLLEQEARNSRVSVGIAPSALQLLLGYAWPGNVRQLRHVLAY
ACAVCEGGTVQVADLPVEVRGEQVAAPTEDRASPERQVVLDALIRHRWKPLPTAQALGIS
RATLYRRVNQLGIDMPGKPRH