Protein Info for PS417_11720 in Pseudomonas simiae WCS417

Annotation: class V aminotransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 423 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details PF00266: Aminotran_5" amino acids 61 to 390 (330 residues), 97.5 bits, see alignment E=8.3e-32 PF22580: KYNU_C" amino acids 330 to 419 (90 residues), 33 bits, see alignment E=4.9e-12

Best Hits

KEGG orthology group: None (inferred from 95% identity to pfs:PFLU2549)

MetaCyc: 63% identical to pyoverdin I decarboxylase monomer (Pseudomonas aeruginosa PAO1)
RXN-20772

Predicted SEED Role

"Pyoverdin biosynthesis protein PvdN, putative aminotransferase, class V" in subsystem Siderophore Pyoverdine

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U2V1 at UniProt or InterPro

Protein Sequence (423 amino acids)

>PS417_11720 class V aminotransferase (Pseudomonas simiae WCS417)
MTDRRTFLKQAGVFAASLPLGAALLPQALAAPATDDPWTGLKQLFNQDPDYLHFSNFLVA
THPKPVREAIERYRAQIDRNPGLAMDWDLQETWKREGQVREWAGRYLKATPPQIALTGST
SEGLAMIYGGIKVRPDQEILTTVHEHYATEYSLDFRVRKEQTQVRKIRLFDSANRVSADE
VLGNIQRNIRPNTRVLGMTWVQSGSGVKLPIGEIGKLVEEHNRNRDDKDRILYVVDGVHG
FGVENLDFPDMHCDFFIAGTHKWMFGPRGTGLVCARDPQNNDVTPMVPTFSEDKDFATVM
TPGGYHAFEHRWAADEAFKLHLQLGKAQVQARIHALNTELKDQLLAHPKIELVTPHSPEL
SAGFTFFRVNGQDSDAVAAYMMKNRVVIDAVDRDVGPVIRTAPGLLNSSAEVQRFMTLLS
QRA