Protein Info for GFF2284 in Xanthobacter sp. DMC5

Annotation: Photosynthetic apparatus regulatory protein RegA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 182 PF00072: Response_reg" amino acids 13 to 122 (110 residues), 82.3 bits, see alignment E=1.4e-27

Best Hits

Swiss-Prot: 72% identical to ACTR_SINMW: Acid tolerance regulatory protein ActR (actR) from Sinorhizobium medicae (strain WSM419)

KEGG orthology group: K15012, two-component system, response regulator RegA (inferred from 95% identity to xau:Xaut_0306)

Predicted SEED Role

"Dna binding response regulator PrrA (RegA)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (182 amino acids)

>GFF2284 Photosynthetic apparatus regulatory protein RegA (Xanthobacter sp. DMC5)
MNEMPEVGDDRSVLIVDDDRSFLQRLARAMEARGFEVTTAETVADGLARVETSAPAYAVV
DMRLGDGTGLDVISALKKNRPGARAIVLTGYGNIATAVTAVKLGAVDYLAKPADADDVVA
ALLANADHKPTPPENPMSADRVRWEHIQRVYELCGRNVSETARRLSMHRRTLQRILAKRA
PR