Protein Info for GFF2278 in Variovorax sp. SCN45

Annotation: ABC transporter, permease protein 2 (cluster 4, leucine/isoleucine/valine/benzoate) / ABC transporter, ATP-binding protein 1 (cluster 4, leucine/isoleucine/valine/benzoate)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 604 transmembrane" amino acids 22 to 45 (24 residues), see Phobius details amino acids 52 to 82 (31 residues), see Phobius details amino acids 96 to 117 (22 residues), see Phobius details amino acids 124 to 141 (18 residues), see Phobius details amino acids 171 to 191 (21 residues), see Phobius details amino acids 219 to 239 (21 residues), see Phobius details amino acids 258 to 282 (25 residues), see Phobius details amino acids 301 to 324 (24 residues), see Phobius details PF02653: BPD_transp_2" amino acids 47 to 314 (268 residues), 117.7 bits, see alignment E=1e-37 PF00005: ABC_tran" amino acids 372 to 530 (159 residues), 99.8 bits, see alignment E=4.1e-32 PF12399: BCA_ABC_TP_C" amino acids 583 to 604 (22 residues), 33.1 bits, see alignment (E = 6.6e-12)

Best Hits

KEGG orthology group: K01995, branched-chain amino acid transport system ATP-binding protein K01998, branched-chain amino acid transport system permease protein (inferred from 75% identity to pna:Pnap_0802)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (604 amino acids)

>GFF2278 ABC transporter, permease protein 2 (cluster 4, leucine/isoleucine/valine/benzoate) / ABC transporter, ATP-binding protein 1 (cluster 4, leucine/isoleucine/valine/benzoate) (Variovorax sp. SCN45)
MEALLKSETAAPAPDKSALRTWGPLALILVLAVLPFLPLPDFWIIQLNYIGIYTLPVLGL
VLLTGVGGLTSFGQAAFVGIGAYTTAYLTVNTGLSPWVTLFIGLALTGISAAIIGAITLR
MSGHYLPLATIAWALSLYYLMGNLDALGKYDGILGVKGLSLFGFEFGQQRFFYGVVWVFA
IVAAFAVIRLLDSRSGRAIRSLAGGSQMAEAMGVNTLRFKIGIFVLAAMLASISGWLFAH
FQRTVNPSPFGLKMGIEYLFMAVLGGAAHVWGAIAGAGVVKLLEDQLQVLLPKLIGTAGS
YELIVFGIMIVLVLKYLPEGLWAFVDRRLPRPRRTVDWQDAKDLPARAKPAAGEVVLDVQ
AIRKTFGGLVAVNDISFQTRAGQIVGLIGPNGAGKSTTFNLVTGVLSLSGGAVRFRGEAI
GGLGARQIAQRGVSRTFQHVKMVADMTVLENVALGAHLRGQRGAIAAMLRTDRQEERALF
REAERQLRRVGMGEYLHELAGNLAMGQQRLLEIARALCADPALLLLDEPAAGLRHKEKEA
LGKVLRQLRDEGMSILLVEHDMGLVMDICDHIVVMEFGTHLMEGTPAQVQNSDKVRAAYL
GTEH