Protein Info for PS417_11595 in Pseudomonas simiae WCS417

Annotation: ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 412 signal peptide" amino acids 1 to 39 (39 residues), see Phobius details PF13458: Peripla_BP_6" amino acids 49 to 391 (343 residues), 296.4 bits, see alignment E=6.6e-92 TIGR03407: urea ABC transporter, urea binding protein" amino acids 50 to 407 (358 residues), 533.1 bits, see alignment E=1.5e-164 PF13433: Peripla_BP_5" amino acids 51 to 409 (359 residues), 428.6 bits, see alignment E=3.1e-132 PF01094: ANF_receptor" amino acids 72 to 321 (250 residues), 27.4 bits, see alignment E=2.7e-10

Best Hits

KEGG orthology group: K01999, branched-chain amino acid transport system substrate-binding protein (inferred from 96% identity to pba:PSEBR_a3691)

Predicted SEED Role

"Urea ABC transporter, urea binding protein" in subsystem Urea decomposition

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UEB0 at UniProt or InterPro

Protein Sequence (412 amino acids)

>PS417_11595 ABC transporter substrate-binding protein (Pseudomonas simiae WCS417)
MDSSLQRSRPMAPRLIRSTPLLALSLLAAALFSQGVLADNEGLAVTPTEVTVGQLHSATG
TMAISETGSIQAERLAIEQINASGGILGRQIKVIQEDGASDWPTFAEKAKKLLVNDKVAA
VFGCWTSASRKAVLPIFEKENGLLYYPTFYEGLEQSKNVIYTGQEATQQILASLDWIAKT
KGAKTFYLVGSDYIWPRTSMKIARKHIENVLHGTVVGEDYYPLGNTQFGSLINKVKLKKP
DVVFAAVVGGSNVAFYKQLNAAGVNSAKQTLLTLSVTEDELLGIGGENMAGFYASMKYFQ
SLDNPNNKAFVEAFKAKYGKDAVIGDVTQAAYLGPWLWKAAVEKAGSFDVDKVVAASPGI
ELKTAPEGYVKIHENHHLWSKSRIGEVQPNGQFKVIYESDLIEPNPFPKGYQ