Protein Info for GFF2270 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: FIG022199: FAD-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 441 transmembrane" amino acids 215 to 236 (22 residues), see Phobius details amino acids 302 to 310 (9 residues), see Phobius details amino acids 393 to 412 (20 residues), see Phobius details PF01494: FAD_binding_3" amino acids 7 to 327 (321 residues), 78.6 bits, see alignment E=2.3e-25 PF12831: FAD_oxidored" amino acids 8 to 169 (162 residues), 32.4 bits, see alignment E=2.6e-11 PF00890: FAD_binding_2" amino acids 8 to 43 (36 residues), 25 bits, see alignment 4.3e-09 PF04820: Trp_halogenase" amino acids 8 to 79 (72 residues), 39.7 bits, see alignment E=1.2e-13 amino acids 98 to 355 (258 residues), 51.4 bits, see alignment E=3.2e-17 PF01266: DAO" amino acids 8 to 41 (34 residues), 29.4 bits, see alignment 2.5e-10 PF13450: NAD_binding_8" amino acids 11 to 46 (36 residues), 33.1 bits, see alignment 2.3e-11

Best Hits

KEGG orthology group: None (inferred from 77% identity to vap:Vapar_2969)

Predicted SEED Role

"FIG022199: FAD-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (441 amino acids)

>GFF2270 FIG022199: FAD-binding protein (Hydrogenophaga sp. GW460-11-11-14-LB1)
MQPEETCDVLVIGGGPAGSTIAALLAREGRKVVLLEKEHHPRFHIGESLLPGNVALFDKL
GVRDQIEKIGMPKFGIEFVPPDLDYCSYVDFAEGWDPSMASAWQVRRSEMDELLFRHAAK
VGAEALEGAKVTEVAFDDDGAGVAAVLDSGEKRRWRARFVVDATGRDTLLANKFKCKEKN
KDHNSTALFGHFRGARRLEGKREGNISICWFEHGWFWFIPLADGTTSVGAVCWAYYLKAR
DKPLKDYFFDTIALCPELHDRLKDATLVDDQVHATGNFAYSSTHATGDRYLMVGDAFTFI
DPMFSSGVFLAMQSGFDGAQFVATALDAPQRLPAARAAYEKRVRVGPRDYSWFIYRVTNP
TIRDMFMHPNNRFKVKQGLMSLLAADIHHGPSYRLSLVMFKLIYYVVSVANWRRTYAGWK
RHRFNIRDMGALRGETIMKAD