Protein Info for PS417_01150 in Pseudomonas simiae WCS417

Annotation: taurine ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 325 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF04069: OpuAC" amino acids 26 to 235 (210 residues), 79.4 bits, see alignment E=6.8e-26 PF13379: NMT1_2" amino acids 26 to 240 (215 residues), 53 bits, see alignment E=9e-18 TIGR01729: taurine ABC transporter, periplasmic binding protein" amino acids 27 to 323 (297 residues), 444.4 bits, see alignment E=1.1e-137 PF12974: Phosphonate-bd" amino acids 49 to 228 (180 residues), 33.8 bits, see alignment E=4.8e-12 PF09084: NMT1" amino acids 52 to 244 (193 residues), 76.4 bits, see alignment E=6.4e-25

Best Hits

Swiss-Prot: 55% identical to TAUA_ECOLI: Taurine-binding periplasmic protein (tauA) from Escherichia coli (strain K12)

KEGG orthology group: K02051, sulfonate/nitrate/taurine transport system substrate-binding protein (inferred from 98% identity to pfs:PFLU0255)

MetaCyc: 55% identical to taurine ABC transporter periplasmic binding protein (Escherichia coli K-12 substr. MG1655)
ABC-64-RXN [EC: 7.6.2.7]

Predicted SEED Role

"Taurine-binding periplasmic protein TauA" in subsystem Taurine Utilization

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7TYI7 at UniProt or InterPro

Protein Sequence (325 amino acids)

>PS417_01150 taurine ABC transporter substrate-binding protein (Pseudomonas simiae WCS417)
MKLLTPLRLLAALSLAGASLFAQAADVTIAYQTTVDPAKVAQADGAYEKATNAKINWRKF
DNGADIIAAIASGDVQIGYLGSSPLTAAITRKVPVETFLVATQIGGAEALVARDGSGING
PQDLIGKKVAVPFVSTGHYSLLAALKHWNIDPSKVTILNLAPPAIIAAWKRGDIDATYVW
DPALGVAKENGKVLITSGELAKFGAPTFDAWIVRKDFAEKHPQIVTAFAKVTLDAYAAYR
KDPQAWLADKGNVDKLVKLSGAKASDIPLLLQGNVYPLAADQVTLLGAPTTQAVTDTAAF
LKEQGKVDAVLPDYAPYISAKFITH