Protein Info for GFF2267 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: L-rhamnose operon transcriptional activator RhaR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 282 PF02311: AraC_binding" amino acids 23 to 146 (124 residues), 72.4 bits, see alignment E=6.2e-24 PF07883: Cupin_2" amino acids 27 to 79 (53 residues), 28.3 bits, see alignment E=2.4e-10 PF12833: HTH_18" amino acids 199 to 275 (77 residues), 77.7 bits, see alignment E=1.4e-25 PF00165: HTH_AraC" amino acids 237 to 276 (40 residues), 46.3 bits, see alignment 6.6e-16

Best Hits

Swiss-Prot: 100% identical to RHAR_SALPA: HTH-type transcriptional activator RhaR (rhaR) from Salmonella paratyphi A (strain ATCC 9150 / SARB42)

KEGG orthology group: K02854, AraC family transcriptional regulator, L-rhamnose operon transcriptional activator RhaR (inferred from 99% identity to sed:SeD_A4444)

Predicted SEED Role

"L-rhamnose operon transcriptional activator RhaR" in subsystem L-rhamnose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (282 amino acids)

>GFF2267 L-rhamnose operon transcriptional activator RhaR (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
VANQLILLKKDFFTDEQQAVTVADRYPQDVFAEHTHEFCELVMVWRGNGLHVLNERPYRI
TRGDLFYIRAEDKHSYTSVNDLVLQNIIYCPERLKLNVNWQAMIPGFQGAQWHPHWRLGS
MGMNQARQVINQLEHESNGRDPLANEMAELLFGQLVMTLKRHRYATDDLPATSRETLLDK
LITALANSLECPFALDAFCQQEQCSERVLRQQFRAQTGMTINQYLRQVRICHAQYLLQHS
PLMISEISMQCGFEDSNYFSVVFTRETGMTPSQWRHLSNQSD