Protein Info for GFF2248 in Sphingobium sp. HT1-2

Annotation: Inner membrane component of TAM transport system

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1401 transmembrane" amino acids 32 to 51 (20 residues), see Phobius details PF04357: TamB" amino acids 1058 to 1401 (344 residues), 203.4 bits, see alignment E=3.6e-64

Best Hits

KEGG orthology group: K09800, hypothetical protein (inferred from 77% identity to sch:Sphch_0253)

Predicted SEED Role

"FIG00635901: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1401 amino acids)

>GFF2248 Inner membrane component of TAM transport system (Sphingobium sp. HT1-2)
MATPPPDSQPPVPPPPAAPPRRRAWDGRWQRWLAGALALALLVVVATLAWLDSAPGHRFL
VSRIAAVSPPSGLRIHVDRIEGSIYRKAVLRGLVLSDPKGRFFDAPRVELDWWPFAWLSN
RLDIDRLVIPQATLHKLPKLNPSERQGPILPGFDIRLMQFSVDRLTVAPAVTGKVELATL
SGDADIRGGRAIIDLSARVIGAEDALNLTLDSRPDDDRFNLAVTVNAPRGGVLAAMAGLN
QDGNLRISGKGRWTRWDGRLAATLVGNPVADLKLGARSGAYTIQGTIEGSAIPGKGLLPR
LASPRLTIGAQGTLADRVVDGRLTLRSAAIDMVADGAIDLRNNAFDNLRVDMNLARPEAL
LKDMRGRDVVAKVRLDGPFAGFGYEYLLTARQLAFGKTQINDVRIDGKGRQAKSGPVLLP
VRLRARSLDGQGDLVAGIVRNFALDGVLQLKGQQIVSNPMPFRSDRLNGKLLVMADLKSG
RYDVGIDGRISGLFIRGLGIVDLDSKLRAAPGANGAFGLSGNAVAKVRRLDNAFLKGLGG
GLPTVRSALALLPGGEIGFSNMKLDAPLISLNAKGVRHRDGTVHLEGNGSHKQYGPVNVV
LDGKIDRPIVHVQLARPMDALGLRDVRGEFLPGADGNYSFTANGGSTLGPFTGEGRILLP
PGGQAVVRVARIAVSGVTASGDIRPVTGGLDGQLLVAGPVSGTIGFQPVGGIQQLKLDLD
ANDASFDGPSTIAVRRGSLDATILLDPDGTSINATAQARGLRVGGMLLGRLDATAALVDG
RGKVSGNLSGQRGRLFDLKGEAQVDLDRVRLSASGTIDKRPIRLTRAALFTRAEDGWRLS
PATISYAGGTLQLAGELGGETTRIEARAQKMPLALLDIAYDNLGLGGMATGTLSYSRPRG
GLPTGKAELRIRGLSRSGLSLSSRPVDVGVNAVLTLDRLATRMVFVADGQTIGRGQALLT
PLISTGSLVERLNGAPLIAQLRFNGTADTLWRLTGVEIVDIAGPVSVTADAHGTLADPVI
TGSLATDNAALNSPVTGMRLRNVKARARFAGAQLVFSSFTANAQNGGSVTGTGNFTFNGI
GGVGMDLAFQADNAALLERDDIAATVTGPLTIRSDGKGGEIGGDVTLNRSRFTMGRAAAV
AQIPELKVIEINRRGEEIERPRAAEPWTMAVKARARNRLTVTGLGLDSEWRADLNIGGTV
TNPAIAGRAELVRGNYEFAGRRFELREGRIQFDGKTPVNPTLDIDAEADVSDLTATIHVG
GTGLKPDISFNSVPSLPQDELLSRILFGTSITNLSAPEALQLASAVGSLQGEGGLDPINA
VRKAAGLDRLRIIAADPTQGQGTSLAAGKYLTRKTYVELISDGQGYSATRMEYQVTRWLS
LLGAISTLGRQSANLRISKDY