Protein Info for GFF2241 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Inner membrane protein YihY, formerly thought to be RNase BN

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 290 transmembrane" amino acids 39 to 62 (24 residues), see Phobius details amino acids 73 to 91 (19 residues), see Phobius details amino acids 103 to 120 (18 residues), see Phobius details amino acids 140 to 164 (25 residues), see Phobius details amino acids 180 to 199 (20 residues), see Phobius details amino acids 211 to 234 (24 residues), see Phobius details amino acids 240 to 268 (29 residues), see Phobius details TIGR00765: YihY family inner membrane protein" amino acids 18 to 275 (258 residues), 352.1 bits, see alignment E=1.2e-109 PF03631: Virul_fac_BrkB" amino acids 29 to 274 (246 residues), 208.4 bits, see alignment E=7.9e-66

Best Hits

Swiss-Prot: 100% identical to YIHY_SALTY: UPF0761 membrane protein YihY (yihY) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K07058, membrane protein (inferred from 100% identity to stm:STM4027)

Predicted SEED Role

"Inner membrane protein YihY, formerly thought to be RNase BN"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (290 amino acids)

>GFF2241 Inner membrane protein YihY, formerly thought to be RNase BN (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MLKTVHQKAGRHTRPVRAWLKLLWQRIDEDNMTTLAGNLAYVSLLSLVPLIAVVFALFAA
FPMFSDVSIQLRHFIFANFMPATGDVIQRYIEQFVANSNKMTAVGACGLIVTALLLMYAI
DSALNTIWRSKRTRPKVYSFAVYWMILTLGPLLAGVSLAISSYLLSLRWASDLNTVIDNV
LHILPLLLSWISFWLLYSIVPTTRVPNRDALVGAFVAALLFEAGKKGFALYITMFPSYQL
IYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYRKLKQAAEQEEADQP