Protein Info for GFF2240 in Sphingobium sp. HT1-2

Annotation: D-xylose proton-symporter XylE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 470 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 50 to 71 (22 residues), see Phobius details amino acids 83 to 101 (19 residues), see Phobius details amino acids 107 to 129 (23 residues), see Phobius details amino acids 147 to 167 (21 residues), see Phobius details amino acids 183 to 202 (20 residues), see Phobius details amino acids 265 to 287 (23 residues), see Phobius details amino acids 303 to 324 (22 residues), see Phobius details amino acids 331 to 351 (21 residues), see Phobius details amino acids 371 to 395 (25 residues), see Phobius details amino acids 407 to 428 (22 residues), see Phobius details amino acids 436 to 455 (20 residues), see Phobius details TIGR00879: MFS transporter, sugar porter (SP) family" amino acids 9 to 467 (459 residues), 339.3 bits, see alignment E=1.8e-105 PF00083: Sugar_tr" amino acids 18 to 468 (451 residues), 362.7 bits, see alignment E=3.1e-112 PF07690: MFS_1" amino acids 22 to 420 (399 residues), 104.2 bits, see alignment E=7.4e-34

Best Hits

Swiss-Prot: 49% identical to GLCP_SYNY3: Glucose transport protein (gtr) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: None (inferred from 91% identity to sch:Sphch_1211)

Predicted SEED Role

"D-xylose proton-symporter XylE" in subsystem Xylose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (470 amino acids)

>GFF2240 D-xylose proton-symporter XylE (Sphingobium sp. HT1-2)
MSEGSAGKVNMAFIAAIVAVATIGGFMFGYDSGVINGTQKGLEAAFDLGKLGIGVNVGAI
LVGSSIGAFGAGRMADIIGRRGVMMLAAILFLVSALLAGAAGSSAIFIIARIIGGLGVGA
ASVISPVYISEVTPASIRGRLSSVQQVMIISGLTGAFVANFVLARYAGGSTAPLWLDFPA
WRWMFWLQAIPAAIYFLALLVIPESPRYLVARGQDERARAVLTKLFGAEEANRKVTEIRA
SLAADHHRPKLSDLIDKASGKVRPIVWAGIGLAVFQQLVGINVVFYYGATLWEAVGFSED
NALQINILSGVLSIGACLGTIMLVDKIGRKPLLLIGSAGMAVTLAIVAYAFSTAVTGADG
GVVLPGHNGLMALIAANLYVIFFNLSWGPIMWVMLGEMFPNQIRGSGLAVAGFAQWIANA
AISVSFPSLAVSPGLVVTYTGYALFAAISFFFVRAMVHETKGRELEDMVG