Protein Info for GFF2228 in Sphingobium sp. HT1-2

Annotation: Hexuronate transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 424 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details transmembrane" amino acids 54 to 73 (20 residues), see Phobius details amino acids 80 to 99 (20 residues), see Phobius details amino acids 106 to 126 (21 residues), see Phobius details amino acids 138 to 162 (25 residues), see Phobius details amino acids 169 to 188 (20 residues), see Phobius details amino acids 228 to 249 (22 residues), see Phobius details amino acids 269 to 289 (21 residues), see Phobius details amino acids 302 to 319 (18 residues), see Phobius details amino acids 324 to 347 (24 residues), see Phobius details amino acids 356 to 382 (27 residues), see Phobius details amino acids 389 to 411 (23 residues), see Phobius details PF07690: MFS_1" amino acids 19 to 374 (356 residues), 186.7 bits, see alignment E=2.9e-59

Best Hits

KEGG orthology group: K08191, MFS transporter, ACS family, hexuronate transporter (inferred from 93% identity to sjp:SJA_C2-03430)

Predicted SEED Role

"Hexuronate transporter" in subsystem Alginate metabolism or D-Galacturonate and D-Glucuronate Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (424 amino acids)

>GFF2228 Hexuronate transporter (Sphingobium sp. HT1-2)
MTTIPKPSGKVRWIVCGLLFAAVVLSYIDRLVLPTLKPDLQARYGWSESGYADLAIWFQA
GYGIAYVAFGRLIDRIGARAGYALAVGLWTVGHVMHIFFTSTAGMLFARIPLAIGEAGTF
PAAIAATNEWFPKKERAFAIGIFNAGSNVGAILTPLIVPVIAVTLGWRWAFILTGLLTVF
WLAAWLGFYRRPREKKGLSAEELAWIEADPQEPARPVKWRTLFRYRQTWAYMTSRFLIDP
VWWTFLFWLPDFFNKQYGVKMLDFGPPLIAVYLLADVGSVAGGWLSSRLMGRGMNINRAR
KTAMFCAGLCALPIAFAAQAPSMWIAVGLIGLACAGHQGFSANVYALPGDLFPRWMAGSV
VGLGGLAGAIGGMLMAKFAGIILETVGSFQPIFIVASCAYLLALLVLHLIVPRYTPVTLS
QEAV