Protein Info for GFF2219 in Sphingobium sp. HT1-2

Annotation: Organic hydroperoxide resistance transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 154 PF22381: Staph_reg_Sar_Rot" amino acids 33 to 116 (84 residues), 69.7 bits, see alignment E=3.7e-23 PF12802: MarR_2" amino acids 42 to 100 (59 residues), 38.2 bits, see alignment E=2.6e-13 PF13463: HTH_27" amino acids 44 to 110 (67 residues), 24.9 bits, see alignment E=4e-09 PF01047: MarR" amino acids 44 to 102 (59 residues), 43.4 bits, see alignment E=5.1e-15

Best Hits

KEGG orthology group: None (inferred from 61% identity to swi:Swit_2956)

Predicted SEED Role

"Organic hydroperoxide resistance transcriptional regulator" in subsystem Oxidative stress

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (154 amino acids)

>GFF2219 Organic hydroperoxide resistance transcriptional regulator (Sphingobium sp. HT1-2)
MTTPAMTAQDTARGALDDFLCFGVYSTGLAFNRLYKPLLDRYGLTYPQYLVMVALARRDD
QTVGELGGQLFLESNTLTPLIKRLEAAALVTRQRDTKDERVVRVRLTQQGQSVAQDVSTC
VPAELMEAVGISIEEIAALNQSLVTLREKLQRAA