Protein Info for PS417_11300 in Pseudomonas simiae WCS417

Annotation: general secretion pathway protein GspE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 472 TIGR02533: type II secretion system protein E" amino acids 3 to 469 (467 residues), 734.9 bits, see alignment E=2e-225 PF22341: GSPE_N1E" amino acids 4 to 64 (61 residues), 30.1 bits, see alignment E=4.2e-11 PF00437: T2SSE" amino acids 99 to 467 (369 residues), 492.8 bits, see alignment E=5.1e-152

Best Hits

Swiss-Prot: 85% identical to HXCR_PSEAE: Probable type II secretion system protein HxcR (hxcR) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K02454, general secretion pathway protein E (inferred from 98% identity to pfs:PFLU2424)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7TWW4 at UniProt or InterPro

Protein Sequence (472 amino acids)

>PS417_11300 general secretion pathway protein GspE (Pseudomonas simiae WCS417)
MSLLPYAWAKSQRILLRPGDQGMLLTVCPSTPGWSISEVHRQFGQTHLEQVRDDELDGLL
TSAYADTGSAAAVVGAAENEVDLDRLMQDMPEITDLLDTQDGAPVIRMINALLTQAARDE
ASDIHIEPYETHSVVRYRVDGTLRDVVSPRKALHGALVSRIKIMAQLDIAEKRLPQDGRI
ALRVAGRPIDIRVSTVPTGHGERVVMRLLDKQAGRLQLETLGMAPQLLARLDTLIRQPHG
IVLVTGPTGSGKTTSLYAALARLDASTSNILTVEDPVEYDLPGISQIQVNAKIDMTFGLA
LRAILRQDPDIIMIGEIRDLETAQIAVQASLTGHLVLATLHTNDAVSAVNRLIDMGVEPF
LLASSLLGVLAQRLVRRLCPHCKQEDPSAPGTWRPVGCAQCNQIGYSGRTGIHELFCVDD
DVRSLIHQGANEQDLRLAARRAGMFSMREDGERWVHSGATAPEEILRVTRDA