Protein Info for GFF2211 in Variovorax sp. SCN45

Annotation: Flp pilus assembly protein RcpC/CpaB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 331 signal peptide" amino acids 1 to 37 (37 residues), see Phobius details TIGR03177: Flp pilus assembly protein CpaB" amino acids 11 to 328 (318 residues), 166.2 bits, see alignment E=4.4e-53 PF08666: SAF" amino acids 53 to 112 (60 residues), 30.4 bits, see alignment E=4.9e-11 PF16976: RcpC" amino acids 114 to 232 (119 residues), 96.5 bits, see alignment E=1e-31

Best Hits

KEGG orthology group: K02279, pilus assembly protein CpaB (inferred from 77% identity to vap:Vapar_4444)

Predicted SEED Role

"Flp pilus assembly protein RcpC/CpaB" in subsystem Widespread colonization island

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (331 amino acids)

>GFF2211 Flp pilus assembly protein RcpC/CpaB (Variovorax sp. SCN45)
MINLTKILAAILVLLAIALGGYAWMLSRQAPAPAVATTGPAAPTKAKEVLVYPVVVAAKA
LPAGEAIPADALRVERLTINPAGAFQDVSVAAGRVPVIDLAEGAPLMENQLVSGLAVRIA
EGERAVAIKADEIMGVGNKIQPGDFVDVFITLKSDGKDVDRSQARLLLSRKRVLAFGSAS
VDGMPSKAPDKAAAQQAQRTEMARTAVLAVPVDEVNRLTIGDASGRLLLALRNPTDMSQP
DPKLFAELPTALQPVQAKTGEPRRAPLEGLDLAQAGLTTADLATGGKGPGVKSPAVEARV
ATAPRRATSAGAHGGLQVEVIRGARSETVSY