Protein Info for GFF2193 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Ribulose bisphosphate carboxylase large chain (EC 4.1.1.39)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02788: RuBisCO_large_N
  • amino acids 30 to 150 (121 residues), 145.2 bits, E=1.1e-46
• PF00016: RuBisCO_large
  • amino acids 161 to 467 (307 residues), 453.6 bits, E=3.2e-140

Best Hits

Swiss-Prot: 89% identical to RBL1A_METPP: Ribulose bisphosphate carboxylase large chain 1 (cbbL1) from Methylibium petroleiphilum (strain ATCC BAA-1232 / LMG 22953 / PM1)

KEGG orthology group: K01601, ribulose-bisphosphate carboxylase large chain [EC: 4.1.1.39] (inferred from 89% identity to mpt:Mpe_A1478)

MetaCyc: 59% identical to CbbL (Synechocystis sp. PCC 6803)

Predicted SEED Role

"Ribulose bisphosphate carboxylase large chain (EC 4.1.1.39)" in subsystem CO2 uptake, carboxysome or Calvin-Benson cycle or Carboxysome or Photorespiration (oxidative C2 cycle) (EC 4.1.1.39)

MetaCyc Pathways

• Rubisco shunt (10/10 steps found)
• Calvin-Benson-Bassham cycle (11/13 steps found)
• ethene biosynthesis V (engineered) (19/25 steps found)
• 1-butanol autotrophic biosynthesis (engineered) (20/27 steps found)
• photosynthetic 3-hydroxybutanoate biosynthesis (engineered) (19/26 steps found)
• oxygenic photosynthesis (12/17 steps found)
• nucleoside and nucleotide degradation (archaea) (2/10 steps found)

KEGG Metabolic Maps

• Carbon fixation in photosynthetic organisms
• Glyoxylate and dicarboxylate metabolism

Isozymes

Compare fitness of predicted isozymes for: 4.1.1.39

Use Curated BLAST to search for 4.1.1.39

Protein Sequence (489 amino acids)

>GFF2193 Ribulose bisphosphate carboxylase large chain (EC 4.1.1.39) (Hydrogenophaga sp. GW460-11-11-14-LB1)
MSNAPTGSTEITDAKKRYSAGVLKYKQMGYWMPDYVPKDTDTLCLFRITPQDGVDPEEAA
AAVAGESSTATWTVVWTDRLTACDSYRAKAYKVQPVPNRPGEYFAWVAYDLILFEEGSIA
NMTASLIGNVFSFKPLKAARLEDIRIPVAYVKTFKGPPTGLVVERERLDKFGRPLLGATT
KPKLGLSGRNYGRVVYEGLKGGLDFMKDDENINSQPFMHWRDRFLFVMDAVNKASAETGE
VKGSYLNVTAATMEDMYERAEFAKELGSVIVMVDLVIGYTAIQSMANWCRKNDMIMHMHR
AGHGTYTRQKNHGVSFRVIAKWLRLAGCDHLHTGTAVGKLEGDPLTVQGYYNVCRDSYTK
TDLPRGLYFDQDWADLKKVMPVASGGIHAGQMHQLIELFGDDVVLQFGGGTIGHPMGIQA
GAVANRVALEAMVKARNEGRDLLQEGPSILKQAAQHCSPLKAALDTWGEISFNYQSTDSS
DYVATPAMA